An introduction to the NIHR RDSYH and the RfPB Programme

1. The NIHR RDS for Yorkshire and the Humber An introduction to the NIHR RDSYH and the RfPB Programme 22nd Sept 2010 Dr Maureen Twiddy

2. To introduce and describe the role of the NIHR RDSYH Briefly introduce the RfPB programme To share hints and tips about the research application process for NIHR applications. Aims of workshop

3. Faculty Associates Investigators &Senior Investigators Trainees Universities Infrastructure Research Clinical Research Networks RDS Research Projects & Programmes NHS Trusts Patients&Public Clinical Research Facilities & Centres Research Units & Schools Research InformationSystems Research GovernanceSystems Systems

4. NIHR Research Design Services Successful research proposals Focus is translational research RfPB has been a key driver

5. Portfolio or Non-Portfolio? • Portfolio – study adopted onto the NIHR Research Portfolio • Advantages: • ‘Kitemark’ of quality • Study attracts supports costs • Benefits of CSP for R&D approvals

6. What gets adopted? • Studies that are funded by NIHR, other areas of Government, and NIHR non-commercial Partners • NIHR Partners are those organisations that: • award research funds as a result of open competition across England with high quality peer review • fund research that is of clear value to the NHS • take account of DH and NHS priorities and needs in their research funding strategies. • Applications for evaluation are made through IRAS (project adoption form) • Non-commercial investigator (NHS or HEI) led studies that are funded by commercial sources • Commercially sponsored studies come under further scrutiny • See http://www.ukcrn.org.uk/index/clinical/portfolio_new/P_eligibility.html for further detail

7. The vision for NIHR RDSYH

8. RDS Staff • Statistics • Health Economics • Randomised control trials • Complex interventions • Qualitative Methods • PPI • Information Specialists

9. Consultations 09_10

10. How can the RDS help researchers? • Focusing ideas and refining the research question • Building an appropriate research team • Involving patients and the public in all stages • Overall research design • Choice and application of research methodologies • How to undertake a literature search • Identifying the most appropriate funding stream • Signposting to other services

11. RDSYH Support: Learning events • Making successful applications to RfPB • Patient and public involvement in research design • Developing a proposal for a systematic review • Searching the literature • Writing research proposals for quantitative service evaluation • Qualitative research methods

12. NIHR Funding Opportunities EME Annual Budget £15m RISC Annual Budget £5m HSR Annual Budget £5m I4I Annual Budget £13m HTA National Budget £88m NIHR CCF RfPB National Budget £25m PHR Annual Budget £10m PGfAR Annual Budget £75m SDO Annual Budget £11m

13. NIHR Funding Opportunities EME Annual Budget £15m RISC Annual Budget £5m HSR Annual Budget £5m I4I Annual Budget £13m HTA National Budget £88m NIHR CCF RfPB National Budget £25m PHR Annual Budget £10m PGfAR Annual Budget £75m SDO Annual Budget £11m

14. Research for Patient Benefit(RfPB) Programme AimsThe main aim of the RfPB programme is to support projects in Health Services Research and Public Health. Projects can be either quantitative or qualitative, and should aim to study the way that NHS services are provided and used evaluate whether interventions are effective and provide value for money examine whether alternative means for providing healthcare would be more beneficial in terms of cost and effectiveness formally assess innovations and developments in healthcare which will benefit of patients.

15. Process Awards up to £250,000 over a 3 year period Response mode – no restriction on topic or clinical area Rolling programme: three decision dates per year (November, February/March, June) Accept submissions at any time, for consideration at next available committee One staged on-line submission via the CCF website Submissions will be peer reviewed which will be presented to the committee

16. http://www.nihr-ccf.org.uk/site/registration/ Register with the CCF website

17. Full application 23 page application form – lot of work Authorised costings (9 pages) Do’s; include direct costs including essential equipment, externally provided tests, reasonable overheads Don’ts; do not include estates costs Needs to be signed-off by Business manager/finance officer Details of any assistance (e.g. RDS)

18. NIHR RfPB Projects in Y&H

19. Things to consider before submitting applications

20. Assessment criteria What assessment criteria do the panel use to make a judgement on applications? Key things that you would consider when assessing an application?

21. Who sees applications? Funding stream secretariat Methodologists NHS Clinicians, commissioners and managers (50% fail “relevance” screen) Peers Other disciplines Service users Conclusion: a lot of different people have to be pleased

22. Assessment criteria Ensure you’re in the scope of the programme Clear/plain English Clear structure Internal peer review will help

23. Best places to spot weakness / inexperience? CTU and network involvement (missing, or token) Inclusion/exclusion criteria (too narrow) Identification and numbers of eligible people (too optimistic) Consent and numbers consenting (vague; too optimistic) Follow up rate (unrealistically high or unacceptably low) Effect size (much too large) Number and type of sites (too narrow; willingness asserted)

24. The research team KEY ISSUE Must be capable of delivery Evidence of track record Diversity of skills Reflective of study Sadly, when NIHR get submissions from twelve clinicians we know that… …a lot of hardworking people JUST WASTED THEIR TIME

25. Be clear of the benefits of your research What is the impact of the study; Locally Nationally On practice Policy. Clearly and explicitly identify benefits for: Patients NHS

26. Patient and Public Involvement Increasingly vital Absence of PPI needs explanation Tokenism spotted and not acceptable ‘Active’ involvement required At one or more stages of the process Having a ‘decision making impact on a key aspect of the research’ Funding for PPI available from RDS

27. Other Costings Inaccurate/unrealisitc Rushed (leading to above!) Research already being done Experience of team/chief investigator Commercial development in disguise ‘no credible chance of patient benefit’

28. Conclusion Right Team Right Funding Stream Careful adherence to criteria Peer review PPI Leave sufficient time Demonstrate that YOU CAN DELIVER ON TIME TO BUDGET

29. Summary Growing number of sources funding for a range of research projects Targeting your research at the most appropriate scheme is the best way to increase your chance of success Examples of types of projects funded http://www.nihr-ccf.org.uk/site/commissionedprojects/default.cfm NIHR RDS for Y&H is here to support researchers Expertise in a range of methodologies Help with more specialised searches for funding via RDS Another source of funding information is RD Info (information from 1381 Funding Bodies offering 5518different awards at time of writing)

30. Sheffield email: rds-yh@sheffield.ac.uk Tel: 0114 222 0828 (general enquiries) Leeds email: rds-yh@leeds.ac.uk Tel: 0113 343 1477 (general enquiries) York email: rds-yh@york.ac.uk Tel: 01904 321358 (general enquiries) www.rds-yh.nihr.ac.uk

31. Questions?