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The MIN mouse : (1.) Heterozygous for the highly penetrant Apc Min allele.

The MIN mouse : (1.) Heterozygous for the highly penetrant Apc Min allele. (2.) Min/Min homozygotes die at gastrulation. (3.) Mice develop numerous (50-200) adenomas in the small intestine, and few (0-3) in the colon. (4.) Death occurs around 5 months of age.

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The MIN mouse : (1.) Heterozygous for the highly penetrant Apc Min allele.

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  1. The MIN mouse: (1.) Heterozygous for the highly penetrant ApcMin allele. (2.) Min/Min homozygotes die at gastrulation. (3.) Mice develop numerous (50-200) adenomas in the small intestine, and few (0-3) in the colon. (4.) Death occurs around 5 months of age. (5.) Tumor multiplicity modulated by genetic background, drugs, and diet.

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