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gadanergili-organo gadarCenili sicocxle!. Tirkmlis transplantacia. Tirkmeli – adamianis ZiriTadi eqskretoruli organo. daSlis produqtebiT mdidari sisxli Tirkmels arteriiT miewodeba da ifiltreba. sisxlis filtratia Sardi Sardi SardsawveTiT Sardis buStSi grovdeba da SardsadeniT gareT gamoiyofa.
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gadanergili-organo gadarCenili sicocxle! Tirkmlis transplantacia
daSlis produqtebiT mdidari sisxli Tirkmels arteriiT miewodeba da ifiltreba • sisxlis filtratia Sardi • Sardi SardsawveTiT Sardis buStSi grovdeba da SardsadeniT gareT gamoiyofa
Tirkmlebi ganlagebulia retroperitonealur sivrceSi, gulmkerdis XI da welis III malebis doneze • Tirkmlis masa 120-200 gr. • sirZe 10-12 sm. • sigane 5-6 sm. • sisqe 3-4 sm.
Tirkmeli Sedgeba gareTa-qerqovani da SigniTa-tvinovani Sreebisagan • Tirkmlis ZiriTad struqturul-funqciur erTeuls warmoadgens nefroni
Tirkmlebis umniSvnelovanesi fiziologiuri roli-homeostazis regulacia • osmoregulacia • volumoregulacia • eleqtrolituri da mJava-tutovani balansis mudmivobis SenarCuneba • azotovani cvlis produqtebis eqskrecia • cilebis, lipidebis, naxSirwylebis metabolizmSi monawileoba • organizmidan toqsikuri nivTierebebis gauvnebelyofa da gamoyofa • hemodinamikis regulacia • inkretoruli funqcia
Tirkmlis mwvave da qronikuli ukmarisoba irRveva Tirmlis funqciebi • wyalmarilovani, azotovani da sxva nivTerebaTa cvla Tirkmlis mwvave ukmarisoba • irRveva filtraciuli, gamomyofi da sekretoruli funqciebi
Tirkmlisqronikuliukmarisobis mizezi SeiZleba iyos: • yvla is daavadeba, romelic iwvevs Tirkmlis gorglebis dazianebas
Tirkmlis qronikul ukmarisobas iwveven Semdegi daavadebebi Tirkmlebis polikistozi arteriuli hipertenzia qronikuli glomerulonefriti, pielonefriti sistemuri wiTeli mglura, hemoragiuli vaskuliti Saqriani diabeti, podagra, amiloidozi
Tirkmlis qronikul ukmarisobas iwveven Semdegi daavadebebi SardkenWovani daava- deba, hidronefrozi Tirkmlis ganviTa- rebis Tandayolili anomaliebi Sardsadenze zemwoli simsivne
TirkmliT CanacvlebiTi Terapiis ori forma transplantacia dializi
Tirkmlis pirveli gadanergva • 1902 w. uremiiT daavadebuls gadaunerges Roris Tirkmeli • 1933 w. gadainerga gardacvlili adamianis Tirkmeli • 1954 warmatebiT gadainerga gardacvlili adamianis Tirkmeli
warmatebuli operaciisTvis ozefmiurem 1990 wels nobelis premia miiRo • swored miureis naSromebi daedo safuZvlad Tanamedrove transplantologias
Tirkmlis gadanergva saqarTveloSi • 1977 w. gadainerga gvamuri Tirkmeli • 1997 w. daarsda transplantologTa asociacia
organoTa donaciis me-12 evropuli dRe TbilisSi • 2010 w. 23 oqtombers Tbilisma pirvelad umaspinZla “organoTa donaciis me-12 evropul dRes” • RonisZiebaSi monawileoba miiRo ormocamde eqim-transplantologma evrosabWos qveynebidan
saqarTveloSi 2000 w. miRebuli kanonis Tanaxmad donori SeiZleba iyos, rogorc cocxali, ise gardacvlili adamiani • recipients SeiZleba gadaenergos mxolod genetikuri naTesavis, meuRlis, an meuRlis naTesavis organo • saqarTveloSi moqmedebs ‘donorTa gacvlis programa’ • organoebiT vaWroba saqarTveloSi xuTidan aT wlamde Tavisuflebis aRkveTiT isjeba
donori-adamiani, romlis sxeulidanac iReben gadasanerg qsovils an organos • sisxlis jgufis Tanxvedra, leikocituri antigenebisa da e.w. jvaredini reaqciis mixedviT • erTmaneTis msgavsi unda iyos donorisa da recipientis masa da asaki • sasurvelia Tirkmlis gadanergva erTi da imave sqesis adamianebs Soris moxdes Tavsebadobis ZiriTadi parametrebi
yvela donorma unda gaiaros fsoqosocialuri gamokvleva, Tirkmlis gacemis motivaciis Sesafaseblad
recipienti-adamiani, romelsac energeba qsovili an organo
gadanergvisaTvis saWiroa recipientis momzadeba • unda mowesrigdes sisxlis bioqimiuri maCveneblebi, arteriuli wneva, gul-sisxlZarRvTa sistemis muSaoba • aucelebelia ganikurnos yvela anTebiTi procesi • sisxlSi eriTrocitebisa da hemoglobinis saTanado donis uzrunvelyofa • donoris Tirkmlis Tavsebadobis dasadgenad unda Catardes antigenebisa da histoSeTavsebis sistemebis kompleqsuri gamokvleva
recipienti, rogorc donori, srulad unda iyos informirebuli yvela mosalodneli garTulebis Sesaxeb
operaciisdawyebamde • xeli unda moaweroT Tanxmobis formaze, romelic adasturebs Tqvens Tanxmobas Tirkmlis gadanergvis operaciaze
operaciismimdinareoba • operaciis dros wamlebis Sesayvanad pacients venaSi udgamen ramdenime kaTeters wveTovaniT • piridan filtvebSi SeyavT mili, romelic SeerTebulia filtvebis xelovnuri ventilaciis aparatTan • akontroleben gulis cemis sixSires, arteriul wnevas, sunTqvas
saoperacio velis kans daamuSaveben Zlieri antiseptikuri xsnariT • eqimi avlbes grZel ganakveTs muclis qvemoT cal mxareze
donoris Tirkmels aTavseben muclis RruSi • donoruli Tirkmlis SardsawveTs uerTeben Sardis buSts • donoruli Tirkmlis arteriasa da venas uerTeben pacientis TeZos arteriasa da venas
donoris marjvena Tirkmeli marcxniv inergeba, xolo marcxena-marjvniv; amiT advili xdeba donoruli Tirkmlis SardsawveTis mierTeba Sardis buStTan
ganakveTs keraven qirurgiuli nakeriT • SeSupebis Sesamcireblad ganakveTis ubanSi Tavsdeba drenaJi • Wrilobas adeben sterilur saxvevs
c Tirkmlis gadanergvis operaciis Semdeg pacients awvenen intensiuri Terapiis an reanimaciis palataSi, mdgomareobis gaumjobesebis Semdeg gadayavT Cveulebriv palataSi
operaciis Semdeg pacients eniSneba medikamentebi, raTa organos mwvave mocilebis reaqcia ar ganviTardes
Sin dabrunebis Semdeg • donorma erTxans Tavi unda aaridos zogierT sakvebs ( comeuls; mwares; cxares; marilians; alkoholur sasmelebs da sxva ) • recipientisaTvis mniSvnelovania naoperaciebi midamos sufTad da mSralad SenarCuneba
Tirkmlis transplantantis daavadebebi • qronikuli mocilebis sindromi • medikamentozuri intoqsikacia • transplantis qronikuli nefropaTia • rekurentuli daavadeba
msofliostatistikisTanaxmad, gadanergili Tirkmlis funqcionirebis maqsimaluri xangrZlivoba 20-30 welia