Eric Niederhoffer SIU-SOM

Jul 26, 2012

140 likes | 357 Views

Vitamins in Neuromuscular Metabolism. Names and roles for vitamins and vitamin-like substancesDeficiencies and sources for vitamins and vitamin-like substancesVitamin A transportRole in pathways (glycolysis, glycogenolysis, PPP)Role in pathways (TCA cycle, gluconeogenesis)Neurotransmitter overv

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Eric Niederhoffer SIU-SOM

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Eric Niederhoffer SIU-SOM

Making basic science clinically relevant for learners: the biochemistry example. Eric Niederhoffer SIU-SOM. Wants and needs Curriculum design, objectives, goals; USMLE Biochemistry as a foreign language Web lessons , resource pages , animations Resource sessions

576 views • 26 slides

Eric Niederhoffer SIU-SOM

What is the role of the pentose phosphate pathway?. Eric Niederhoffer SIU-SOM. NADPH production Glutathione reduction (E), fatty acid/cholesterol synthesis (L) Glycolytic intermediates Fructose-6-phosphate, glyceraldehyde-3-phosphate Ribose-5-phosphate

219 views • 6 slides

Eric Niederhoffer SIU-SOM

Writing USMLE-style questions for SIU-SOM exams. Eric Niederhoffer SIU-SOM. What is USMLE style? The General Process Resources to Use Examples to Evaluate. Outline. Three main types Single best answer Sequential item sets Extended matching (not discussed). USMLE Style.

390 views • 23 slides

Eric Niederhoffer SIU-SOM

A Primer on Writing Effective Multiple-Choice Questions. Eric Niederhoffer SIU-SOM. General Guidelines Bad and Ugly and Good Single Best Answer Formats Resources to Use Examples to Evaluate. Outline. Focus on important concepts, not trivial facts

409 views • 22 slides

Eric Niederhoffer, Ph.D. SIU-SOM

Biochemical basis of acidosis and alkalosis: e valuating acid base disorders. Eric Niederhoffer, Ph.D. SIU-SOM. Approach h istory physical examination d ifferentials clinical and laboratory studies compensation Respiratory a cidosis a lkalosis Metabolic acidosis alkalosis

626 views • 29 slides

Eric Niederhoffer SIU-SOM

A 38-year-old woman is brought to the physician because of frequent falls, increasing confusion, and incontinence. How does ethanol ingestion cause nutrition problems?. Eric Niederhoffer SIU-SOM. Cellular processing Pathway perturbations Malate-aspartate shuttle Glycerol-3-phosphate shuttle.

217 views • 7 slides

Eric Niederhoffer SIU-SOM

A 38-year-old woman is brought to the physician because of frequent falls, increasing confusion, and incontinence. How does ethanol ingestion cause nutrition problems?. Eric Niederhoffer SIU-SOM. Ketone body processing overview Ketogenesis and ketone body utilization Clinical features.

246 views • 7 slides

Eric Niederhoffer SIU-SOM

A 59-year-old man with a history of diabetes and alcohol abuse is brought to the emergency room in a semiconscious and minimally responsive state. How are glucose, triacylglycerols , and amino acids normally metabolized and what happens in diabetes?. Eric Niederhoffer SIU-SOM.

683 views • 37 slides

Eric Niederhoffer SIU-SOM

A 4-year-old African boy is brought in by his adoptive parents who say that he has pain in his limbs and does not want to walk. A 40-year- old man complains of progressive exertional shortness of breath. How are CO 2 , NO, and O 2 processed and transported?. How is heme synthesized?.

224 views • 9 slides

Eric Niederhoffer SIU-SOM

SSB End of Unit Review. Eric Niederhoffer SIU-SOM. Submitted Questions. Which enzymes are inhibited by elevated NADH versus which steps cause elevated NADH ? Inhibited: Dehydrogenases Elevated: ADH, AlDH Specific inhibitory/activating substrate interactions with PFK1, PFK2

223 views • 8 slides

Eric Niederhoffer SIU-SOM

A 54-year-old female presents to her family physician's office with a 2 week history of pain and numbness in her left hand. A 7-year-old boy is brought to the physician with a recent history of decreased activity.

370 views • 17 slides

Eric Niederhoffer SIU-SOM

Year Two Review Part 1. Eric Niederhoffer SIU-SOM. Outline. Newborn screening Glycolytic pathway Pentose phosphate pathway Fructose pathway Pyruvate metabolism and citric acid cycle β-Oxidation Urea cycle Branched-chain amino acids Aromatic amino acids Cholesterol pathway

488 views • 30 slides

Eric Niederhoffer, Ph.D. SIU-SOM

Year Two Review. Eric Niederhoffer, Ph.D. SIU-SOM. Pyrimidine and purine synthesis including salvage and degradation Glycogen storage disorders Lysosomal storage disorders Heme synthesis and degradation including oxygen binding/unloading of heme Integration of metabolism

404 views • 23 slides

Eric Niederhoffer, Ph.D. SIU-SOM

Pyrimidines and Purines. Eric Niederhoffer, Ph.D. SIU-SOM. Pyrimidine and purine synthesis Pyrimidine and purine salvage/degradation Pathway disorders. Outline. Pyrimidine and Purine Synthesis. HCO 3 - + Gln. R5P. CPSII. RPK. CP. Asp. PRPP. Oro. Gln. UMPS. Gly. UMP.

193 views • 6 slides

Eric Niederhoffer, Ph.D. SIU-SOM

585 views • 28 slides

Eric Niederhoffer, Ph.D. SIU-SOM

Year Two Review Part 2. Eric Niederhoffer, Ph.D. SIU-SOM. Pyrimidine and purine synthesis including salvage and degradation Glycogen storage disorders Lysosomal storage disorders Heme synthesis and degradation including oxygen binding/unloading of heme Integration of metabolism

359 views • 20 slides

Eric Niederhoffer SIU-SOM

A 54-year-old woman presents to her family physician's office with a 2 week history of pain and numbness in her left hand. A 19-year-old man, lying flat on a stretcher and wearing a hard cervical collar, arrives in the Emergency Room. Do you administer NSAIDs or steroids to these patients?.

245 views • 11 slides

Eric Niederhoffer SIU-SOM

A 4-year-old African boy is brought in by his adoptive parents who say that he has pain in his limbs and does not want to walk. What affects the normal functions of an erythrocyte?. Eric Niederhoffer SIU-SOM. RBC structure size, spectrin , channels Metabolism

394 views • 15 slides

Eric Niederhoffer SIU-SOM

A 38-year-old woman is brought to the physician because of frequent falls, increasing confusion, and incontinence. A 29-year-old woman is brought to the physician because of thought abnormalities. What is the role of vitamins in metabolic pathways?. Eric Niederhoffer SIU-SOM.

463 views • 16 slides

Eric Niederhoffer SIU-SOM

Regulation of Phosphofructokinase-1: Too Much of a Good Theme?. Eric Niederhoffer SIU-SOM. Problem-based learning using electronic patient cases Organ-system, integrated disciplines Specific example - diabetes mellitus/alcoholic ketoacidosis Learning Issues

241 views • 7 slides

Eric Niederhoffer, Ph.D. SIU-SOM

ERG Review 2014. Eric Niederhoffer, Ph.D. SIU-SOM. What is the effect of diabetes on glycogen? What is the difference between the PFK2-F26BPase activity/regulation in the liver versus in the heart ? How is glucokinase regulated?

195 views • 6 slides

SIU TRR

Gamma-ray Large Area Space Telescope. SIU TRR. GLAST Large Area Telescope: Presented by G. Haller SLAC haller@slac.stanford.edu (650) 926-4257. Contents. Introduction Overview Significant Changes since CDR Objectives Status Requirements/Verification EGSE and Test-Procedures

476 views • 37 slides

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