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The Electron Transport System mitochondrion illustration lifted from The Biology Colouring Book

The Electron Transport System mitochondrion illustration lifted from The Biology Colouring Book. The Electron Transport System and the Chemiosmotic Hypothesis. recall that mitochondria have an outer and an inner membrane the inner membrane is extensively folded into cristae

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The Electron Transport System mitochondrion illustration lifted from The Biology Colouring Book

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  1. The Electron Transport Systemmitochondrion illustration lifted from The Biology Colouring Book

  2. The Electron Transport System and the Chemiosmotic Hypothesis • recall that mitochondria have an outer and an inner membrane • the inner membrane is extensively folded into cristae • it is actually the movement of H+ that creates most of our ATP!

  3. ETS • recall that mitochondria have an outer and an inner membrane • the inner membrane is extensively folded into cristae (KRISS-tee or KRISS-tay) • the space between the inner and the outer membrane acts as a reservoir

  4. Changing level of detail... • At first appraisal, ATP comes from the breakdown of glucose to CO2 and H2O. • Recall that old favourite: • C6H1206 + O2 ----> CO2 + H20 + energy • Glycolysis shows the detail of the beginning of the process but actually accounts for only 2 of the possible 36 ATP. • The Krebs cycle accounts for 4 more ATP but also produces NADH and FADH2 • The ETS shows how NADH and FADH2 are used • but it is finally the proton pump (the chemiosmotic hypothesis) that finally shows where the majority of the ATP are produced. • (KEM-ee-oz-MOT-ik)

  5. ETS 1 • NADH gives electrons to acceptor 1 • by this process NADH is oxidized to NAD+ • acceptor 1 also takes in 2 H+ -- one from NADH, and one from the surrounding solution

  6. ETS 2 • Acceptor 1 is oxidized as it passes the electrons to acceptor 2 • acceptor 2 has the extra 2 protons • note the movement of the electrons to acceptor 2

  7. ETS 3 • Acceptor 2 becomes oxidized when it loses its protons andelectrons • acceptor 2 passes its electrons to acceptor 3 • protons are released into the intermembrane space

  8. ETS 4 • Electrons continue to move along the system • acceptor 5 is reduced • more protons will be added to acceptor 5 and begin the transport process

  9. ETS 5 • Acceptor 6 becomes reduced...

  10. ETS 6 • When acceptor 7 is oxidized, it releases more protons into the intermembrane space • FADH2 additionally reduces acceptor 5 -- more protons and electrons are added to the system

  11. ETS 7 • Acceptor 8 finally releases the electrons • electrons are accpted by oxygen -- which reduces the oxygen • protons from the matrix are added to the reduced oxygen • this forms water!

  12. ETS 8 • Protons are added to oxygen to form water • protons must be replaced in order to continue production of water • protons come back into the matrix space through the F1 complex • this movement generates ATP

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