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Cardiovascular Disease & Hypercholesteremia. By Grant Blackmon, Peichi Hai, Jessica Ruiz, April Stahl. Cardiovascular Disease. Some form of disease of the heart and blood vessels In developed counties, accounts for more deaths than any other disease Heart attack, stroke, aneurysm
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Cardiovascular Disease & Hypercholesteremia By Grant Blackmon, Peichi Hai, Jessica Ruiz, April Stahl
Cardiovascular Disease • Some form of disease of the heart and blood vessels • In developed counties, accounts for more deaths than any other disease • Heart attack, stroke, aneurysm • Risk factors • Age, gender, family history • High LDL, Low HDL cholesterol • Hypertension • Diabetes • Diet and physical activity level • Smoking
Hypercholesteremia (aka High LDL cholesterol) • Low density lipoprotein cholesterol • LDL carry cholesterol to cells where it can build up as plaque in the arteries • The higher the LDL the greater the risk of developing atherosclerosis • HDL is different from LDL, it is the “Healthy cholesterol” and LDL is the “Less healthy cholesterol” • The higher the HDL and the lower the LDL, the lower the risk is for CVD and hypercholesteremia
Atherosclerosis • Hardening of the arteries • Accumulation of soft, fatty, streaks in the inner walls of the arteries (especially at branch points) • Becomes plaque-hard fibrous and can damage artery walls making them hard and narrow • Most people have well developed plaque by age of 30 • Caused by diet high in saturated fat • Aggravated by: • High LDL • Hypertension • Cigarette smoking • Viral and bacterial infections
Dietary Recommendations to help prevent CVD • Lower intakes of saturated fats and trans-fats • Increase unsaturated fat intake • American Heart Association recommends 2 meals of fish per week • Increase consumption of fruits and vegetables • Increase complex carbohydrates • Soluble fiber binds to cholesterol and bile in the intestines • Soy products and plant sterols might decrease CVD • Maintain healthy weight • Limit alcohol • Avoid tobacco