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Quality Metrics In CRRT. Dr Prabh Nayak Lead Consultant for CRRT, Liver, Kidney & Small Bowel Transplant Birmingham Children’s Hospital, UK. Where are we?. BCH. 31 bedded PICU with approx 1500 admissions annually
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Quality Metrics In CRRT Dr Prabh Nayak Lead Consultant for CRRT, Liver, Kidney & Small Bowel Transplant Birmingham Children’s Hospital, UK
BCH 31 bedded PICU with approx 1500 admissions annually Children’s hospital with all major subspecialities represented (renal, liver, cardiac surgery, ECLS, haem-onc, neurosurgery, trauma, burns, metabolic, transplant) CRRT service model: PIC driven and PIC delivered 50-60 patients receive CVVH/CVVHDF per year
Quality in CRRT To be able to deliver a consistent service with minimal deviation from the standard & minimise variation in practice with minimal complications. Standards & guidelines To the right patient At the right time In the right setting Using the right equipment By the right people Knowledge sharing & improvement
Quality Improvement Metrics Outcomes - Circuit life - Circuit downtime - Time to initiate in time-critical conditions (hyperammonaemia) - Ability to provide intra-operative CRRT cover Safety - Any human factors issues? Cost Improvement Process (Vascath, CVVH solutions) Morbidity and mortality case reviews; Audit against standards Service improvements Educational preparedness: Wet labs, simulation sessions
Fluid Overload and outcomes Gillespie et al, Pediatr Nephrol (2004) 19:1394-1999 Kaplan-Meier survival estimates, by percentage fluid overload category
Randomised Evaluation of Normal vs Augmented Level (RENAL) therapy • 1500 critically ill adults • CVVHDF • 25 ml/kg/hour • 40 ml/kg/hour
Where speed of initiation is of the essence Change of provision of service Many of these patients retrieved from referring hospitals Pre-primed circuit Senior ready for Vascath insertion Small numbers but ticking time-bombs! Need to decrease the time delay between admission & filtration Hyperammonaemia Year Numbers 2010 5 2011 5 2012 5 2013 7 2014 3 2015 2 Grand Total 27
Bridging The Gap: Improving Patient Safety Through Targeted In-Situ Simulation Training Nayak PP, Kidd N, Osborne-Ricketts B, Martin J, Heward Y Pediatric Critical Care Medicine: May 2014 - Volume 15 - Issue 4 (=proof of high quality care and excellent outcomes)
Bridging The Gap: Improving Patient Safety Through Targeted In-Situ Simulation Training Nayak PP, Kidd N, Osborne-Ricketts B, Martin J, Heward Y Pediatric Critical Care Medicine: May 2014 - Volume 15 - Issue 4 (=proof of high quality care and excellent outcomes)
PICANET (Paediatric Intensive Care Audit Network, UK) dataset collection from 2015
What does the future hold? Timing of initiation of CRRT & role of biomarkers? Drug PK studies on extracorporeal circuit Technological innovations in circuit sizes Subspecialised CRRT teams Shared learning from pooled data; multi-centre research