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Fat or bone ? The answer is in the Wnt

Fat or bone ? The answer is in the Wnt. Osteoscoop - Issue N°93 - August 2009. Common bone marrow mesenchymal progenitors. a. Adipogenesis. PPAR . K9. K9. Active PPAR- : target gene expressed. Common bone marrow mesenchymal progenitors. WNT5a. a. b. CaMKII. +. SETDB1. NLK.

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Fat or bone ? The answer is in the Wnt

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  1. Fat or bone ?The answer is in the Wnt Osteoscoop - Issue N°93 - August 2009

  2. Common bone marrow mesenchymal progenitors a Adipogenesis PPAR K9 K9 Active PPAR-: target gene expressed

  3. Common bone marrow mesenchymal progenitors WNT5a a b CaMKII + SETDB1 NLK Osteoblastogenesis + Other kinases Other kinases Adipogenesis SETDB1 NLK PPAR PPAR K9 K9me K9 K9me Active PPAR-: target gene expressed Active SETDB1: target gene inhibited

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