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Lesson 13. Artemisinin and Taxol. Learning Objectives: To explain where artemisinin is derived from and how it can be used To explain where taxol is derived from and how it can be used. Artemisinin. Artemisinin Used in Chinese medicine From the plant Artemisia annua
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Lesson 13 Artemisinin and Taxol • Learning Objectives: • To explain where artemisinin is derived from and how it can be used • To explain where taxol is derived from and how it can be used
Artemisinin • Artemisinin • Used in Chinese medicine • From the plant Artemisia annua • Used in the treatment of malaria • Kills Plasmodium, and stops it reproducing inside the Mosquito • However only active for a few hours
ACT • ACT is used where the parasite has developed a resistance to particular antimalarials • Synthesised Arteminsinin last longer in the body and is cheaper to produce • Can also be used in the treatment on cancer
Taxol • Isolated from the Pacific yew tree • Used in the treatments of some cancers, as it stops the cells from dividing • It is a slow growing tree, only a small amount of taxol can be extracted which kills the tree in the process • PACLITAXEL found in needles of European Yew Tree • Producing enough Paclitaxel to meet the demand is costly
Limited supplies • What are the options available if supplies of a medicinal plant are limited?
Worksheet - Artemisinin-based combination therapy Artemisinin and Taxol (use internet)