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TOXOPLASMOSIS

TOXOPLASMOSIS. A Risk In Pregnancy. What is Toxoplasmosis?. It is an infection caused by the parasite Toxoplasma gondii. What causes Toxoplasmosis?.

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TOXOPLASMOSIS

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  1. TOXOPLASMOSIS A Risk In Pregnancy

  2. What is Toxoplasmosis? • It is an infection caused by the parasite Toxoplasma gondii

  3. What causes Toxoplasmosis? • The protozoan Toxoplasmosis gondii, is a coccidian, obligate, intracellular parasite responsible for zoonotic infections in man and other mammals

  4. Life Cycle: • Two phases • Intestinal and extraintestinal

  5. Toxoplasmosis gondii • Oocysts- Only members of the cat family shed oocysts

  6. Toxoplasmosis gondii • Trophozoites- Tachyzoites are the actively proliferating trophozoites, which are observed during the acute stage of infection

  7. Toxoplasmosis gondii • Tissue cysts: Tissue cysts are found most commonly in the brain and in skeletal and cardiac muscle but can occur in any organ

  8. Signs and Symptoms: • Fever • Sore throat • Sore muscles • Tiredness • Swollen glands • Temporary blurred vision or loss of vision

  9. Diagnosis: • Serological tests • Polymerase chain reaction (PCR) • Histological demonstration of the parasite and or its antigens (i.e. immunoperoxidase stain) • Isolation of the organism

  10. Treatment: • Treatment should be developed in consultation with an obstetrician and infectious disease specialist • Combinations of anti-toxoplasmosis medications (plus leurovorin) • Hospitalization may be necessary

  11. Prevention: • Wear gloves when handling soil • Wash hands with soap and water after outdoor activities • When preparing raw meat, wash any cutting boards, sinks, knives and other utensils that touched the raw meat thoroughly with soap and hot water to avoid contaminating other foods • Cook all meats thoroughly

  12. Prevention: • Keep cats indoors and feed them dry or canned food rather than allowing them to have access to wild birds and rodents

  13. Prevention: • Clean litter box everyday (because the parasite found in cat feces needs one or more days after it is past to become infectious) • Thoroughly wash hands after cleaning litter box

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