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Acute Upper GI Bleed:. Case 1. 64/C/M presented to the A&E with c/o SOBOE, giddiness and lethargy. He gives a history of passing out black tarry stools yesterday. He has been taking diclofenac sodium regularly due to bilateral knee pains.
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Case 1 • 64/C/M presented to the A&E with c/o SOBOE, giddiness and lethargy. • He gives a history of passing out black tarry stools yesterday. • He has been taking diclofenac sodium regularly due to bilateral knee pains. • He has also drinking alcohol regularly, i.e. 2 large bottle of beers daily.
What other physical signs are helpful to determine the cause of GI bleed?
Physical examination • The patient was found to be drowsy, with M5V3E3 (GCS 11/15) • BP was 95/70 mm Hg • HR 110 bpm • Peripheries was cold and clammy • Pulse was feeble • SpO2 95%
What is the causes of the low GCS? • What is the significance of the vital signs recorded?
You find that he has 8 spider naevis, absence of axillary hair and gross ascites. • He has a flapping tremor. • He also has multiple bruising over the extensor surfaces of his arms.
What could be the other cause of his low GCS? • State the stages of hepatic encephalopathy.
Suddenly, he develops haemataemesis. • Do you insert a Ryle’s tube? State your reasons for doing so.
You check the vital signs again : • BP 84/50 mm Hg • HR 150 bpm • GCS M3V2E1 (6/15) • SpO2 89%
Why has the vital signs worsened? • Why has he become more hypoxic?
What do you do now? • List down your approach to stabilizing this patient.
Investigation results • TWC 13.5 • Hb 6.0 • MCV 80 • MCH 30 • Plt 500 • Explain the results above. • Would you expect hypochromic microcytic anemia?
APTT 40 • PT 15 • INR 1.8 • What are the possible causes?
Urea 28 • Creat 140 • Na 130 • K 3.7 • Explain the results above.
TP 60, alb 23 • ALT 878 • ALP 30 • Explain the results.
RBS 3.0 • Why?
What blood products do you want to give and why? • What is the target Hb in this patient?
What is the definitive treatment of this patient? • Are there any drugs which helps reduce bleeding?
Case 2 • 60 year old man presents with 1 week history of malaena and shortness of breath? • On examination he his pale and cachexic. • Hb 9.0g/dL MCV 60 MCH28 • PR showed malaena, examination of the abdomen was unremarkable. • BP 120/80 mm Hg • HR 99 bpm
What could be the possible causes of his UGIB? • What investigations would you send?
Would you transfuse him with blood? • What are the indications for blood transfusion? • How fast would you transfuse the blood? • Do you need to give IV Frusemide as well?
OGDS showed a Forrest IIc ulcer. • What does this mean?
How can the ulcer be treated endoscopically? • What drugs should the patient be given?
Patient asks you what are the risks for OGDS. What do you say?