220 likes | 452 Views
Anatomy, Physiology and Pathology of the lung. The heart and lung block. Airway Anatomy. Human Lung. Anatomy. Lobes. Bronchopulmonary Segments. Alveolus. Type 1 and Type 11 cells. Surfactant. Physiology. Air in and Air out Gas exchange Saturations Alveolar-arterial gradient
E N D
Physiology • Air in and Air out • Gas exchange • Saturations • Alveolar-arterial gradient • Metabolic • Angiotensin 1 to 2 conversion • Eicosanoid metabolism
Pathology • Think Anatomy • Trachea • Bronchus • Alveolus • Endothelium • Interstitial space • Blood vessels • COPD • Respiratory Failure • O2 and oxygen therapy
COPD • Pink puffer or Blue Blotter
Respiratory Failure • Respiratory failure is present if PaO2 is less than 8 kPa - 60 mmHg. • It is sub-classified into one of two types of respiratory failure based on the level of PaCO2: • Type 1 respiratory failure: • PaCO2 is less than 6.5 kPa • PaO2 less than 8 kPa • Type 2 respiratory failure: • PaCO2 is greater than 6.5 kPa • PaO2 is less than 8 kPa
O2 and oxygen therapy • Patients with chronic hypoxia from chronic lung disease • Poor PaO2 and good sats • Acute unwell hypoxic patients need 100% oxygen