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G93A. 100K. 30K. G93A+DBH. ***. 50K. 75K. 20K. 40K. ATP level (relative luminescence units). ATP level (relative luminescence units). 50K. 30K. ATP synthesis (relative luminescence units). 10K. 25K. Rot. Mal. 20K. Rot+DHB. Mal+DHB. 10K. 0. 0. 0. 3. 10. 30. 0. 10.
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G93A 100K 30K G93A+DBH *** 50K 75K 20K 40K ATP level (relative luminescence units) ATP level (relative luminescence units) 50K 30K ATP synthesis (relative luminescence units) 10K 25K Rot Mal 20K Rot+DHB Mal+DHB 10K 0 0 0 3 10 30 0 10 30 100 0 Rotenone (nM) Malonate (mM) 0 5 10 15 20 (Min) Tg G93A Tg G93A+DHB ** 200 150 ATP synthesis rate (RLU/100s/mg protein) 100 50 0 A B C D