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Acne ( propioni bacteria) Azithromycin Doxycycline Clindamycin (topical only)

N.meningitidis Ceftriaxone - children and adults Cefotaxime - neonates Ampicillin Chloramphenicol N. gonorrhea Ceftriaxone Cefotaxime Ciprofloxacin Spectinomycin.

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Acne ( propioni bacteria) Azithromycin Doxycycline Clindamycin (topical only)

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  1. N.meningitidisCeftriaxone- children and adultsCefotaxime- neonatesAmpicillinChloramphenicolN. gonorrheaCeftriaxoneCefotaxime CiprofloxacinSpectinomycin

  2. Pseudomonas aeruginosaePiperacillin+ gentamicin – other than UTCeftazidime+ gentamicin- - do-Aztreonam ,ImipenemCiprofoxacin- preffered in UTI

  3. H. influenzae, M. cattarrhalis AmoxicillinCefaclorCefuroximeaxetilCefprozilCefiximeClarithromycin, azithromycinImipenem

  4. Staph. AureusMehicillinCephazolineVancomycinClindamycin MacrolidesBacitracin- topicalImipenem

  5. S. pyogenes, S. pneumoniaePenicillin vCephalexinClarithromycin, azithromycinBacteroidesfragilisMetronidazoleCefoxitinClindamycinImipenem

  6. ClostridiumdifficileMetronidazoleVancomycinImipenemProphylaxis for surgery a) staph. Aureus; staph. Epidermidiscefazolinevancomycin (mrsa) b) bacteroidesfragiliscefoxitinclindamycin

  7. Diabetic foot infections with osteomyelitisp. aeruginosae, staph. Aureus, b. fragilispiperacillin/ tazobactamticaracillin/ clavulanateampicillin/ sulbactamimipenem/ cilastatinvancomycinaminoglycosides ciprofloxacinclindamycin- s.aureus & b.fragilis* combination therapy often includes clindamycin in addition to these antibiotics.Clindamycin is often used together with ciprofloxacin

  8. Infected burnsMafenide acetate – p. aeruginosae Silver sulphadiazine- p. aeruginosaeBacitracin- staph. AerusAminoglycosidesOsteomyelitisCiprofloxacinClindamycin (s.aureus, b.fragilis)

  9. BrucellaDoxycycline(mild cases)Doxycycline+ streptomycin or rifampin(severe cases) Ciprofloxacin Streptomycin & gentamicinRifampin TMP-SMXMycoplasmapneumoniaeDoxycycline or ciprofloxacin- adultsMacrolides- children

  10. Legionella (Legionnaires' disease)Azithromycin- highly effectiveQuinolones- highly effective Severely ill pts azithromycin or ciprofloxacin with rifampin. Tetracycline(doxycycline, minocycline)- alternative TMP-SMX- alternative. * Erythromycin, the former choice has been replaced by more potent & less toxic antibiotics.Newermacrolides are preffered. Problem with erythromycin: excessive volume load, GI intolerance and ototoxicity.

  11. Acne (propioni bacteria)AzithromycinDoxycyclineClindamycin(topical only)

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