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Osteoporosis. Rockaway Townsquare Walkers Wednesday May 10, 2006 Rocco Simmerano, MD. What is Osteoporosis?. Low bone mass, deterioration of bone tissue and bone fragility Affects 25 million Americans Results in 1.5 million fractures per year
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Osteoporosis Rockaway Townsquare Walkers Wednesday May 10, 2006 Rocco Simmerano, MD
What is Osteoporosis? • Low bone mass, deterioration of bone tissue and bone fragility • Affects 25 million Americans • Results in 1.5 million fractures per year • Medical costs associated with osteoporosis exceed $10 billion dollars annually
How does it happen? • Balance between bone made and bone broken down • Too little bone mass at skeletal maturity • Too much bone loss after menopause BONE FORMATION BONE LOSS = Osteoporosis
Female Post-menopausal Family history Caucasian Over age 65 (men too) Thin build Estrogen deficiency Dietary factors Sedentary Smoking (past or present) Alcohol use Coffee or caffeinated beverages Risk Factors
Diagnosis • DEXA scan (dual-energy x-ray absorptiometry) • Measured against standard values • Measured in the hip and spine • < 1 standard deviation (SD) Normal • 1-2.5 SD Osteopenia • > 2.5 SD or fracture Osteoporosis • Lab tests
Who Should Be Tested? • Perimenopausal and postmenopausal women • Age > 65 (men and women) • Multiple risk factors • Anyone with a “fragility” fracture • Already being treated (to gage the effect of treatment)
Treatment BONE FORMATION • Increase Bone Formation BONE LOSS
Decrease Bone Loss Treatment BONE LOSS BONE FORMATION
Treatment for Men • Calcium—1,000 mg/day • Vitamin D—400-800 IU/day • Nutrition • Exercise • Impact • Strength • Balance
Treatment for Women • Same as for men • Medications • Hormones • Anti-bone loss • Fosamax • Bone forming agents • experimental
Resources • National Osteoporosis Foundation • 202-223-2226 • www.nof.org • National Institutes of Health Osteoporosis and Related Bone Diseases • 800-624-2663 • www.osteo.org