Training

1. Training Essential nutrients for your health magnes direct Denk+ magnes active Denk 02.2015

2. Contents magnesdirect Denk magnesactive Denk Product Information Key Selling Points Posology & Ingredients Target Group Effects on Muscles, Nervesand Heart Magnesium & Diabetes Magnesium & Migraine Magnesium & Pre-eclampsia Cramps Goodtoknow Other Denk Nutrition Products Complementary Treatments Train the Brain References Click on thetitle toredirecttothepageswithfurtherinformation! Click toreturntothispage!

3. 1. magnesdirect Denk & magnesactive Denk

4. 2. Key SellingPoints • Very good compliance - only 1 stick per day • Easy consumption without water • 2 different concentrations (300 mg and 400 mg) for individual requirement • magnes direct: fruity lemon and orange flavour • magnes active: fruity raspberry flavour • Contributes to a normal energy-yielding metabolism1 • Beneficial to a normally functioning nervous system and muscle function • Effective cramp prophylaxis1 • Fast supply of magnesium to heart, nerves & muscles2

5. 3. Posology & Ingredients • INTAKE • The recommendedintakeis1 stick per day • Easy consumption- withoutwater Recommendations INGREDIENTS * Magnesium= Magnesiumoxide • Fast resorption • Fast supply of magnesium to • muscle, heart and nerves

6. Train theBrain List some key selling points of magnes direct Denk and magnes active Denk • Good compliance (1 daily, easy consumption without water) • Fast supply of magnesium to muscles, heart, nerves • Contributes to a normal energy-yielding metabolism • Beneficial to a normally functioning nervous system and muscle • function • Effective cramp prophylaxis • Different concentrations for individual requirement

7. 4. Target Group magnesactive Denk: 300 mg Magnesium

8. 4. Target Group magnesdirect Denk: 400 mg Magnesium

9. 5. Effects on Muscles MUSCLES • Good for regular sport • Contributes to leading an activelifestyle • Increases efficiencyof muscles/ strength • Crampprophylaxis Easy consumption - even during sports

10. 5. Effects on Nerves NERVES • Contributes to the efficiencyof nerves • Helps prevent physical and mental stress • Calmingeffect on the nervous system • Contributes to reducing chronic inflammatory stress levels and improves sleep quality

11. 5. Effects on theHeart HEART • Complementary treatment for heart disease • Promotes blood pressure • regulation & arrhythmia • prevention • Helps reduce inflammation, • thereby improving • cardiovascular health

12. Train theBrain What is the target group for magnes direct Denk? • Active people • People with physical or mental stress • Men > 14 years • Women 14 – 18 years • People on diet • Pregnant & breastfeeding women 14 – 18 years

13. 6. Magnesium & Diabetes • Low serum magnesium levels are associated with a higher prevalence of • metabolic syndrome and type 2 diabetes (diabetes mellitus) • Higher dietary magnesium intake is associated with a lower risk of developing • metabolic syndrome • CLINICAL TRIAL: • Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects • Double blind, placebo-controlled randomized trial • 52 normomagnesaemic, overweight, insulin-resistant subjects • Magnesium supplementation over 3 months (300 mg/day) • Result: Magnesium supplementation over 6 months resulted in a significant • improvement of fasting plasma glucose and insulin sensitivity • compared to placebo

14. 7. Magnesium & Migraine • People with migraines often have lower levels of magnesium • Magnesium may reduce the frequency of migraine attacks • by 41.6 % compared to 15.8 % to those on placebo. • RECOMMENDATION: 200-600 mg magnesium per day 400 mg Magnesium

15. 8. Magnesium & Pre-eclampsia • Pre-eclampsia is a condition with hypertension, proteinuria and • oedema, occuring in about 6-8 % of all gestations over 20 weeks. • Magnesium has been successfully used for decades in the management of • pre-eclampsia to prevent eclamptic seizures. • Reduces the risk of eclampsia by half compared with placebo • Preferred over diazepam or phenytoin for the treatment of eclampsia Signs & Symptoms: • High blood pressure • Fluid retention • Swelling (swollen hands, feet, face) • Persistent headaches If hypertension or other listed symptoms occur Contact your doctor immediately!

16. 9. Cramps • Leg cramps are reported in up to 60 % of adults and can cause • severe pain and sleep disturbance1 • Older adults • Elderly people have a relatively low dietary intakes of magnesium • Intestinal magnesium absorption tends to decrease with age2 • Elderly people lose muscle mass, remaining muscle may get • overstressed more easily • Athletes • If pushing their limits of endurance • Muscle cramps as a symptom of other medical conditions

17. Train theBrain magnes direct Denk for diseases- list some indications! • Pre-eclampsia • Leg cramps • Diabetes, metabolic syndrome

18. 10. GoodtoKnow • How to avoid a muscle cramp ? • Don’t forget the warm-up phase before exercising • Stretch before, during and especially after working out • Pay attention to sufficient intake of water • Keep to a balanced nutrition • Increase your workout step by step, don’t overstrain your muscles and bones

19. 10. Nice toKnow ANTI STRESS TIPS • Take a walk outside • Sport (ex. Meditation, Yoga) • Treat yourself to something (ex.dinner, massage) • Drink sufficient fluids(ex. chamomile tea) • Reduce stress with time management ANTI STRESS NUTRITION • Wholemeal • Cocoa • Fruits • Nuts (sunflower • seed & walnuts) • Soybeans + Calming effect on nerves

20. Train theBrain How can you decrease your stress levels? • Anti Stress Tips: Time management, be physically active • drink sufficient fluids, treat yourself • Anti Stress Nutrition: Wholemeal, cocoa, fruit, nuts, • soybeans

21. 11. Other Denk Nutrition Products FOR FATHERS -TO-BE may change your (family) life FOR MOTHERS -TO-BE

22. 12. Other Denk Nutrition Products active CALCIUM SUPPLEMENT FOR GROWTH AND MAINTENANCE OF BONES AND TEETH FAST IRON SUPPLY

23. 12. ComplementaryTreatments INDICATION: • Reduces insulin resistance in non-diabetic • subjects • Prevents from developing metabolic • syndrome + or GlimepirideDenk MetforminDenk

24. 12. ComplementaryTreatments INDICATION: Cardiovascular diseases • Complementary treatment for heart disease • Promotes blood pressure regulation & • arrhythmia prevention + Nifedi-Denk AtenololDenk Captopril+HCTDenk Vera-Denk Carvedi-Denk Ena-Denk Amlo-Denk Ena+HCTDenk CaptoprilDenk Losar-Denk CoLosar-Denk Valsar-Denk CoValsar-Denk

25. 12. ComplementaryTreatments INDICATION: Breast cancer • Cramp prophylaxis during emesis • Calms nervous system + • Cancer associated iron anaemia is • very common • Less tiredness and fatigue + or AnastrozoleDenk LetrozoleDenk

26. 13. Train theBrain How can you decrease your stress levels? What is the target group for magnes direct? Magnesium in diseases! List some indications! Name some key selling points of magnes direct and magnes active!

27. 13. Train theBrain • 1) Anti Stress Tips: Time management, be physically active drink sufficient fluids Anti Stress Nutrition: Wholemeal, Cocoa, Fruit, Nuts, Soybeans • 2) • Active people • People with physical or mental stress • Men > 14 years • Women 14 – 18 years • People on diet • Pregnant & breastfeeding women 14 – 18 years • 3) Pre-eclampsia, leg cramps, diabetes, metabolic syndrome • 4) Key selling points • Fast supply of magnesium to muscles, heart, nerves • Contributes to a normal energy-yielding metabolism • Beneficial to a normally functioning nervous system and muscle function • Effective cramp prophylaxis

28. 14. References • Bioverfügbarkeit von organischen und anorganischen Verbindungen, Sighart Golf, Pharmazeutische Zeitung online, 07/2009 • Magnesium in disease, Geiger et al., Clinical Kidney Journal 2012 5 (Suppl1): 125-138 • German/Austrian/Swiss Nutrition Society (DGE, ÖGE, SGE), Referenzwerte für die Närhstoffzufuhr, Neuer Umschau Buchverlag, Neustadt a. d. Weinstraße, 1. Auflage, 5., korrigierter Nachdruck (2013) • U.S. department of Health and human services, National Institutes of Health, Magnesium – Fact Sheet for Health Professionals, 2013 • Deutsche Migräne- und Kopfschmerzgesellschaft (German Society for Migraine and Headaches), Akuttherapie und Prophylaxe der Mrigräne, 2008 • U.S. Department of Health & Human Services, Canadian Headache Society guideline for migraine prophylaxis, 2013 • Magnesium, dt.Rheumaklinik2012 • Mooren et al, Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects, Diabetes ObesMetab 2011, 13: 281-284 • Magnesium, a treatment for leg cramps? Health News and Evidence, 28 Feb 2014 • http://lpi.oregonstate.edu/infocenter/minerals/magnesium/University of Maryland, Medical Center, Migraineheadache,07/2013 • http://umm.edu/health/medical/altmed/condition/migraine-headache • Pharmazeutische Zeitung online, Magnesiumsulfat beugt Krämpfen vor, 28/2014 • http://lpi.oregonstate.edu/infocenter/minerals/magnesium/

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