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acetylcholine. a. GDP. GTP. GTP. extracellular. Inositol 1,4,5, trisphosphate IP 3. Phosphotidylinositol 4,5, bisphosphate PIP 2. Diacylglycerol DAG. muscarinic acetylcholine receptor. 7 membrane-spanning domains. 6. 7. phospholipase-C. 2. Plasma membrane. 5. 3. 1. 4.
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acetylcholine a GDP GTP GTP extracellular Inositol 1,4,5, trisphosphate IP3 Phosphotidylinositol 4,5, bisphosphate PIP2 Diacylglycerol DAG muscarinic acetylcholine receptor 7 membrane-spanning domains 6 7 phospholipase-C 2 Plasma membrane 5 3 1 4 G-protein Gq g a b IP3 Receptor/channel complex Fluid & electrolyte secretion Ca2+ Endoplasmic reticulum intracellular