40 likes | 162 Views
Supplemental Table 1:. Knight et al – Supplementary Table. A. B. n.s. n.s. **. Fold apoptosis induction. -. -. +. +. SIRT1 siRNA. AROS 2 siRNA. Mock. -. -. AROS 1 siRNA. +. +. Fold apoptosis induction. Knight et al – Supplementary Figure 1. HCT116. mRNA expression (%).
E N D
Supplemental Table 1: Knight et al – Supplementary Table
A B n.s. n.s. ** Fold apoptosis induction - - + + SIRT1 siRNA AROS 2 siRNA Mock - - AROS 1 siRNA + + Fold apoptosis induction Knight et al – Supplementary Figure 1
HCT116 mRNA expression (%) SIRT1 mRNA Lamin AC mRNA AROS mRNA siRNA HCT116 p53-/- MCF7 mRNA expression (%) mRNA expression (%) SIRT1 mRNA SIRT1 mRNA Lamin AC mRNA Lamin AC mRNA AROS mRNA AROS mRNA siRNA siRNA WI-38 MCF10A mRNA expression (%) mRNA expression (%) SIRT1 mRNA SIRT1 mRNA Lamin AC mRNA Lamin AC mRNA AROS mRNA AROS mRNA siRNA siRNA Knight et al – Supplementary Figure 2
A Etoposide and TSA Control Control UV-C Treatment p53 50kDa K382Ac 50kDa * β-actin 37kDa B *** *** *** *** Fold apoptosis vs. Mock Mock Mock SIRT1 Mock Mock SIRT1 AROS AROS siRNA UV-C irradiation Etoposide and TSA Condition Knight et al – Supplementary Figure 3