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?????. infectioninfectious diseasecolonizationfacultative pathogenopportunistic organism. ??????????????????? host ??? organism. symbiosiscommensalismtrue parasitism. classification of disease producing organism. Extracellular parasiteFacultative intracellular parasiteobligate intracellula
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1. Pathophysiology of infectious disease Wilawan Toonde,PharmD
2. ????? infection
infectious disease
colonization
facultative pathogen
opportunistic organism
3. ??????????????????? host ??? organism symbiosis
commensalism
true parasitism
4. classification of disease producing organism Extracellular parasite
Facultative intracellular parasite
obligate intracellular parasite
5. Class of human endoparasites and their habitats
6. Class of human endoparasites and their habitats
7. Class of human endoparasites and their habitats
8. ????????? 1. ?????? ?????????
2. ???????????????? ????????? ??? ??????????????????????
3. ??????????????????? (vertical transmission)
4. ??????????????? host ???? reservior (zoonotics)
9. Host defense mechanism 1. non-specific immunity
2. specific immunity
10. non-specific immunity ???????????????????????????????
physical barrier
chemical barrier
bacterial interference
????????????????????????????????
11. ??????????????????????????????? physical barrier
skin, mucous membrane
desquamation
reflex
mucocillary transport system
12. ??????????????????????????????? chemical barrier
lactic acid - glycolipid
fatty acid - mucus
HCL - lysozyme
spermine
13. ??????????????????????????????? bacterial interference
propioibacterium
S.epidermidis, diptheroid
S.viridans
anaerobic bacteria
14. ???????????????????????????????? 1. phagocytic defense
2. NK cell
3. complement system
4. natural Ab
5. IFN
15. specific immunity acute inflammation subacute inflammation * (granulation tissue ??? collagen tissue) chronic inflammation (collagen ????????? scar)