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EPILEPSY

EPILEPSY. INTRODUCTION. Neurological disorder Constant epileptic seizures Over excitation of electro chemical process In adults and children. TYPES OF SEIZURE. There are two types of seizures Focal seizure or partial seizure Generalized seizures. TYPES OF EPILEPSY. Residual epilepsy

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EPILEPSY

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  1. EPILEPSY

  2. INTRODUCTION • Neurological disorder • Constant epileptic seizures • Over excitation of electro chemical process • In adults and children

  3. TYPES OF SEIZURE • There are two types of seizures • Focal seizure or partial seizure • Generalized seizures

  4. TYPES OF EPILEPSY • Residual epilepsy • Process epilepsy • Non-hereditary epilepsy

  5. SYMPTOMS • Seizures • Unconsciousness • Weakness • Nervousness • Staring

  6. Normal Process of Nerve Impulse

  7. Molecular Basis • Insult to brain tissue • Abnormal influx of Ca2+and K+ions • Electrical activity of neurons permanently changed • GABA receptors at post synaptic membrane inhibited • Cells over-fire • Conduction of altered signals

  8. GABA receptors • GABA receptors work to prevent hyper excitation • Open up inhibitory channels • Import Cl- ions inside cells • Inhibition of these receptors leads to violent seizures

  9. GABA Receptors

  10. Anti-epileptic DrugsMechanism of Action

  11. TREATMENT • Epilepsy can be treated by • Medication • Surgery

  12. ROLE OF BIOTECHNOLOGY • Biotechnology plays their role in: • Gene Therapy • Drug Usage

  13. GENE THERAPY FOR EPILEPSY

  14. Research question • Can any effective vaccines be developed for epilepsy?

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