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This study explores the rescue of behavioral deficits in MeCP2-deficient mice through the re-expression of MeCP2 in astrocytes. Results suggest that astrocytes play a crucial role in mitigating such deficits. The findings shed light on potential therapeutic targets for Rett syndrome.
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Partial behavioural rescue after re-expression of MeCP2 in astrocytes. DT Lioy et al.Nature000, 1-4 (2011) doi:10.1038/nature10214