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Cytogenetics The study of : chromosome number, chromosome structure,

Cytogenetics The study of : chromosome number, chromosome structure, chromosome function and behavior in relations to gene inheritance, chromosome organization and expression. Chromosome : A structure composed of DNA and proteins that bears part of the genetic information of the cell.

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Cytogenetics The study of : chromosome number, chromosome structure,

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  1. Cytogenetics • The study of : • chromosome number, • chromosome structure, • chromosome function and behavior in relations to gene inheritance, • chromosome organization and expression Chromosome : A structure composed of DNA and proteins that bears part of the genetic information of the cell

  2. History of cytogenetics

  3. Early chromosome observation using a simple microscope

  4. Recent history (Age of Molecular Cytogenetics) • Gene localization (in situ) • Details of chromosome structure • Studies of genomes • Role of various chromosome regions is realized • Artificial chromosomes are made • Single chromosomes are purified • etc

  5. Three Stages of Genetics Research • Classical Genetics • CytoGenetics • Molecular Genetics

  6. Organization of DNA into Chromosomes

  7. Tools of Cytogenetics Eyepiece Tube Revolving nosepiece Objective Lenses Specimen Stage Iris control Condenser lever Condenser Condenser centering Filters Auxiliary lens Focus control Iris diaphragm Illumination

  8. Thank you

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