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Comprehensive Guide on Weight Management Drugs: Principles, Guidelines, and Treatment Overview

Explore the latest treatment principles, evidence-based recommendations, and guidelines for weight management drugs, including anorexiants, neurotransmitter reuptake inhibitors, sympathomimetics, and lipase inhibitors. Learn about indications, mechanisms of action, nonpharmacologic and pharmacologic treatments, patient monitoring, and crucial patient education.

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Comprehensive Guide on Weight Management Drugs: Principles, Guidelines, and Treatment Overview

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  1. Chapter 70 Weight Management

  2. Drug Overview • Anorexiants • Mixed neurotransmitter reuptake inhibitor • Sympathomimetic • Lipase Inhibitors  • Indications

  3. Mechanism of Action • sibutramine • phentermine • orlistat

  4. Treatment Principles • Standardized Guidelines • U.S. Preventive Services Task Force: Guidelines for screening for obesity in adults, revised 2003. • National Heart, Lung, and Blood Institute at NIH: Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults, 2003

  5. Treatment Principles • Evidence-Based Recommendations • Cardinal Points of Treatment • Nonpharmacologic Treatment • Diet • Exercise • Behavior • Surgery

  6. Treatment Principles • Pharmacologic Treatment • NHLBI guidelines • Role of diet and exercise • sibutramine • phentermine • orlistat • Herbal and OTC preparations • Evaluation of patients who have taken dexfenfluramine or fenfluramine

  7. Treatment Principles • How to Monitor • Patient Variables • Geriatrics • Pediatrics • Pregnancy and lactation • Patient Education

  8. Anorexiants • sibutramine (Meridia) • Contraindications • Warnings • Precautions • Pharmacokinetics • Adverse effects • Drug interactions • Dosage and administration

  9. Anorexiants • phentermine (Fastin, Ionamin) • Contraindications • Warnings • Precautions • Adverse effects • Dosage and administration

  10. Lipase Inhibitors • orlistat (Xenical, Alli [OTC]) • Contraindications • Warnings • Precautions • Overdosage • Dosage and administration

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