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Motifs of Protein Structure

Motifs of Protein Structure. Adapted from “Introduction to Protein Structure” by Branden & Tooze. Adapted from “Introduction to Protein Structure” by Branden & Tooze. a -helix is a dipole moment. Adapted from “Introduction to Protein Structure” by Branden & Tooze.

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Motifs of Protein Structure

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  1. Motifs of Protein Structure

  2. Adapted from “Introduction to Protein Structure” by Branden & Tooze

  3. Adapted from “Introduction to Protein Structure” by Branden & Tooze

  4. a-helix is a dipole moment. Adapted from “Introduction to Protein Structure” by Branden & Tooze

  5. Adapted from “Introduction to Protein Structure” by Branden & Tooze

  6. 2 1 3 Adapted from “Introduction to Protein Structure” by Branden & Tooze

  7. antiparallel b-sheet Adapted from “Introduction to Protein Structure” by Branden & Tooze

  8. Adapted from “Introduction to Protein Structure” by Branden & Tooze

  9. parallel b-sheet Adapted from “Introduction to Protein Structure” by Branden & Tooze

  10. 5 4 2 3 1 1 3 2 4 5 Adapted from “Introduction to Protein Structure” by Branden & Tooze

  11. Loop regions are at the surface of protein molecules Adapted from “Introduction to Protein Structure” by Branden & Tooze

  12. myoglobin Adapted from “Introduction to Protein Structure” by Branden & Tooze

  13. myoglobin triosephosphate isomerase Adapted from “Introduction to Protein Structure” by Branden & Tooze

  14. Topology diagram aspartate transcarbamoylase flavodoxin: redox protein plastocyanin: electron carrier Adapted from “Introduction to Protein Structure” by Branden & Tooze

  15. helix-turn-helix motif Adapted from “Introduction to Protein Structure” by Branden & Tooze

  16. Calcium-binding motif Troponin-C: a muscle protein Adapted from “Introduction to Protein Structure” by Branden & Tooze

  17. Calcium-binding motif Adapted from “Introduction to Protein Structure” by Branden & Tooze

  18. Conformational change of calmodulin upon peptide binding

  19. b-hairpin motif bovine trypsin inhibitor snake venom erabutoxin Adapted from “Introduction to Protein Structure” by Branden & Tooze

  20. Greek key motif staphylococcus nuclease Adapted from “Introduction to Protein Structure” by Branden & Tooze

  21. b-hairpin motif ? Greek key motif Adapted from “Introduction to Protein Structure” by Branden & Tooze

  22. b-a-b motif right hand left hand Adapted from “Introduction to Protein Structure” by Branden & Tooze

  23. Large polypeptide chains fold into several domains Adapted from “Introduction to Protein Structure” by Branden & Tooze

  24. domains are built from structural motifs triosephosphate isomerase Adapted from “Introduction to Protein Structure” by Branden & Tooze

  25. protein structure P53 domain DNA-binding domain motif sheet-turn-helix a-helix & b-sheet & turn secondary structure primary structure linear chain

  26. simple motifs combine to form complex motifs Adapted from “Introduction to Protein Structure” by Branden & Tooze

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