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Sickle Cell Anemia: Understanding the Molecular Biology (http://peptide.ncsa.uiuc.edu/tutorials). Sickle Cell Anemia (SCA) is an inherited blood disorder. It affects about 72,000 Americans (see the National Center for Biotechnology Information website for detail facts).
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Sickle Cell Anemia: Understanding the Molecular Biology(http://peptide.ncsa.uiuc.edu/tutorials) • Sickle Cell Anemia (SCA) is an inherited blood disorder. It affects about 72,000 Americans (see the National Center for Biotechnology Information website for detail facts). • The SCA tutorial, developed in collaboration with teachers, looks at the mutation in hemoglobin that causes this disease. The tutorial utilizes the Biology Workbench as well as the Protein Explorer (http://www.proteinexplorer.org), a tool to make visual exploration of protein structure more accessible to students and teachers. The purpose of the tutorial is two-fold: • Provide students with opportunities to learn how to search databases for DNA and protein sequences and then how to align and manipulate these sequences. • Gain a deeper understanding about the molecular biology of SCA, an extremely common and painful disease.
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