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Pulmonary arterial denervation in patients with PAH

Pulmonary arterial denervation in patients with PAH. Shao-Liang Chen, MD, FACC, FSCAI Nanjing First Hospital, Nanjing Medical University, China. Anatomy of pulmonary artery. Segmentation of PA. PAP during occlusion of basal trunk. PAP during occlusion of interlobar.

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Pulmonary arterial denervation in patients with PAH

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  1. Pulmonary arterial denervation in patients with PAH Shao-Liang Chen, MD, FACC, FSCAI Nanjing First Hospital, Nanjing Medical University, China

  2. Anatomy of pulmonary artery

  3. Segmentation of PA

  4. PAP during occlusion of basal trunk

  5. PAP during occlusion of interlobar

  6. Design of ablation levels

  7. Devices of ablation

  8. Change of PAP during occlusion of interlobar after PADN

  9. Sympathetical labeling

  10. Study flowchart March 2012~ January 2013 PADN-1 PADN-2 Consecutive Randomized 23 PAH 25 CHF pts 21 PAH with 3-m F/U

  11. Table 1. Baseline characteristics in all patients

  12. Table 2. Echocardiographic measurements in two groups

  13. Table 3. Hemodynamic measurements by right heart catheterization

  14. Table 4. Assessment of functional capacity

  15. Tips and pitfalls of PADN

  16. In conclusion PADN around the bifurcation level of main pulmonary artery is safe and effective for PAH Significant improvement of hemodynamics and functional capacity was monitored after PADN procedure

  17. Thanks for your attention!

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