1 / 13

Testosterone

Testosterone. SONG. T is elevated during periods of elevated aggression. T implant increases song rate. Hunt et al, 1997. T receptors found in song system. T is usually elevated during periods of elevated aggression. Seasonal Changes in Aggression, T and E 2. ?.

malise
Download Presentation

Testosterone

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Testosterone SONG

  2. T is elevated during periods of elevated aggression

  3. T implant increases song rate Hunt et al, 1997

  4. T receptors found in song system

  5. T is usually elevated during periods of elevated aggression

  6. Seasonal Changes in Aggression, T and E2 ? Wingfield & Hahn, 1994

  7. aromatase Block hormone synthesis or hormone receptor, measure song • Song Sparrows in Fall • Treatment: • Flutamide: blocks androgen receptor • ATD: blocks aromatase • Test • Play song on birds territory to Simulate Territorial Intrusion • Measure Song production in response Soma et al, 1999

  8. Song Sparrows in Fall Treatment: Control (vehicles) Fadrazol: another aromatase inhibitor Fadrazol + estrogen Rescue effect? aromatase Estrogen or Testosterone? + E2 Soma et al, 2000

  9. E2 receptors found in song system

  10. aromatase Neurosteroid Hypothesis • Steroid precursors released from adrenal or gonad • Made into active steroids in the brain DHEA Soma and Wingfield 2001

  11. HVC volume aromatase Song production DHEA Effects of DHEA? Soma et al, 2002, 2004

  12. Why Neurosteroids?

  13. -DHEA is elevated in spotted antbird -DHEA increases during aggressive encounters

More Related