1 / 18

IMPLANTASI

IMPLANTASI. Definisi : Mammalia = blastosis bersarang dalam rahim  hub. Timbal balik Selaput Ekstra Embrio – Selaput Lendir Rahim Unggas/mammalia bertelur : blastosis melekat pada yolk  embrio berkembang di luar tubuh induk

manton
Download Presentation

IMPLANTASI

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. IMPLANTASI

  2. Definisi : • Mammalia = blastosis bersarang dalam rahim  hub. Timbal balik Selaput Ekstra Embrio – Selaput Lendir Rahim • Unggas/mammalia bertelur : blastosis melekat pada yolk  embrio berkembang di luar tubuh induk • Blastosis aktif = penjuluran kaki palsu (pseudopodia / serat-serat protein menembus epitel rahim) • Rahim aktif = implan jar. Otot / tumor (progestasi) • Blastosis dan rahim sinkron  kegagalan (TE)

  3. PROSES IMPLANTASI IndukBlastosol Serum Prot., Glukosa, P & Cl K+ & Bikarbonat mempermudah tropoblas melekat pada SLR karbonik anhidrase as.karb. CO2 & O2 Implantasi

  4. JENIS-JENIS IMPLANTASI • Superficial (sentral) blastosis di lumen rahimkelinci, karnivora, ungulata • Eksentrik blastosis di kripta / lipatan SLR rodensia • Profundal (intertitial) blastosis menembus & berkembang dlm endometrium manusia, kelelawar & marmut

  5. Kegagalan implan  kematianembrio dini (early death emryonic/EDE)  hari 27: masa kritis bagi kehidupan embrio • EDE : domba = 20 – 30 %, babi = 25 – 40 % • FAKTOR-FAKTOR EED 1. Umur Induk - makin dewasa makin baik - dewasa : muda  73 : 33 % meski Conceptio Rate / CR sama

  6. 2. Temperatur • Secara eksperimental  tahap awal paling cepat terpengaruh  hasil variasi • Embrio domba = perub. mekanisme regulasi metabolik & sintesa protein  embrio lemah (mampu tumbuh) tapi / saat implan 3. Nutrisi - ( - ) nutrisi 7 – 21 = 15 % - ( - ) selenium & iodin = meningkatkan kematian • glikogen, lemak, reruntuhan sel & leukosit histotrof terutamaglisin, alanin, taurin & glutamin dibutuhkan embrio

  7. 4. Hormonal • Progesteron  hormon utama thd perub. Preimplantasi – bunting • Progesteron rendah  menurunkan daya hidup embrio dalam rahim • Kadar < 100 g ( dlm Cl ) tak mempertahankan kelangsungan hidup embrio pada sapi • Injeksi 100 mg dapat meningkatkan daya hidup embrio (7 hari fertilisasi) 5. Kontaminasi Kuman • Menggagalkan implantasi a / infeksi o / jasad renik • Kontaminasi = menembus zp bersama spermatozoa embrio melalui media biakan (Ricketsia, protozoa, klamidia & virus (blue tangue / domba), babi = paruovirus, pseudorabies, vesicular stomatitis, african swine fever, food & mouth disease (PMK) & cytomegalo virus

  8. 6. Immunologis • Embrio alograf dg induk (antigen)  susunan genetika khas yang berbeda • Embrio memproteksi diri ( zigotin ) menekan sistem kekebalan induk bersifat lokal dlm rahim 7. Faktor-Faktor Lain : - musim - variasi individual - inbreeding - obesitas

More Related