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Anesthesia for Neurosurgery. H HOSSEINI MD. SKULL. BRAIN. FORAMEN MAGNUM. The Vertebral Column Or Spinal Column. Neurophysiology. ICP< 15cmH2o CBF= 15-20% of C.O.=50ml/100gr CMRO2=3-3.8 ml/100gr CSF production=500-600 ml/day Brain+CSF+blood =1200-1500 ml Normal ICP=15-20 cmH2o
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Anesthesia for Neurosurgery H HOSSEINI MD
Neurophysiology ICP< 15cmH2o CBF= 15-20% of C.O.=50ml/100gr CMRO2=3-3.8 ml/100gr CSF production=500-600 ml/day Brain+CSF+blood=1200-1500 ml Normal ICP=15-20 cmH2o 1mmHg↓↑PaCO2 from40 mmHg→ ↓↑ 1ml/100gr/mint CBF 1◦C↓T under 37◦C→7%↓CBF
CEREBRAL PERFUSION PRESSURE CPP=MAP-ICP or CVP