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Neurosurgery Review for Medical Student. 17 Febuary 2552. Stroke. ผู้ป่วยหญิงอายุ 50 ปี ขณะดูโทรทัศน์ที่โซฟา มีอาการปวดท้ายทอย อย่างมาก อาเจียน ซึมลง PE : GCS 13, no motor weakness, stiff neck +ve จงให้การวินิจฉัย Pontine hemorrhage Cellebellar hemorrhage Subarchnoid hemorrhage
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Neurosurgery Reviewfor Medical Student 17 Febuary 2552
Stroke • ผู้ป่วยหญิงอายุ 50 ปี ขณะดูโทรทัศน์ที่โซฟา มีอาการปวดท้ายทอย อย่างมาก อาเจียน ซึมลง PE : GCS 13, no motor weakness, stiff neck +ve จงให้การวินิจฉัย • Pontine hemorrhage • Cellebellar hemorrhage • Subarchnoid hemorrhage • Basal ganglion hemorrhage • Intraventricular hemorrhage เฉลย C
Stroke • Ischemic VS hemorrhagic • Ischemic syndrome ต่าง ๆ • Hemorrhagic disease • Hypertensive hemorrhage • Amyloid angiopathy • SAH from ruptured aneurysm • Ruptured AVM • (อื่น ๆ – bleeding tumor, coagulopathy, parasite, vasculitis)
Stroke • Ischemic VS hemorrhagic • Hemorrhagic stroke มักมี sign of IICP (ปวดหัว อาเจียน ซึมลง) • Ischemic stroke มักมาด้วย sudden neurodeficit • Hemiparesis • Apasia / apraxia • Amaurosis fugax • Onset แยกไม่ได้ • Clinical แยกไม่ได้ 100% need investigation = CT
Stroke • Ischemic stroke • MCA: Hemiparesis, contralateralhemisensory loss, aphasia • ACA: Paresis and sensory loss of contralateral lower extremity • PCA: Homonymous hemianopia with macular sparing • Basilar: Cranial nerve signs – diplopia, facial weakness, vertigo, dysarthria
Stroke • Hemorrhagic stroke • Hypertensive ICH • Ruptured cerebral aneurysm • Ruptured AVM • Amyloid angiopathy • Bleeding tumor • Coagulopathy
Stroke • Hypertensive ICH • Hypertension > 90% • IICP signs and symptoms (headache, vomiting, ↓consciousness) • Common site: • Basal ganglion – Hemiparesis, Aphasia (dominant hemisphere) • Thalamus – hemianesthesia • Cerebellar – ataxia, cerebellar sign +ve • Pontine – pinpoint pupil
Stroke • Hypertensive ICH • Antihypertensive drugs • SBP > 200 IV antihypertensive • SBP > 180 or MAP > 130 • IICP suspected monitor ICP keep CPP 60-80 mmHg • No IICP suspected modest ↓ BP to MAP 110 or 160/90 • Surgery VS Medical treatment • Recommendation: cerebellar hemorrhage > 3 cm (class I) AHA guideline 2007
Stroke • Ruptured cerebral aneurysm • “Worst headache of my life” • With or without neurodeficit • Stiffneck / nuchal rigidity • CT: Subarachnoid hemorrhage • Common sequelae: • Rebleeding • Hydrocephalus • Vasospasm
Stroke • Ruptured cerebral aneurysm • Key point of management • Refer to neurosurgeon ASAP (for clipping to prevent rebleeding) • If clinical suspected but negative CT LP ดู xanthochromia • Investigation of choice: 4 vessels angiography (alternative: CT angiography (CTA), MRA)
Stroke • Ruptured AVM • Young age** • Lobar hemorrhage • Non-hypertension • Investigation: angiography • Risk rebleeding 2-3%/y • Management: • Surgery – excision • Embolization • Radiosurgery
Stroke • Investigation in intracerebral hemorrhage • Consider • Angiography • CT angiography In • Young age (< 45) • Non hypertension • Uncommon site (Lobar)
Stroke • Amyloid angiopathy • Old age • Non-hypertension • Lobar hemorrhage • No special investigation needed
Trauma • ผู้ป่วยชายอายุ 50 ปี ขับรถยนต์ชนจักรยานยนต์ สลบไป 10 นาที ตื่นมารู้เรื่องดี หน่วยกู้ภัยนำส่งรพ. ตรวจร่างกายแรกรับปกติ อีก 2 ชั่วโมงซึมลง GCS E1V2M5, pupils right 3 mm, left 5 mm SRTL คิดถึงภาวะใดมากที่สุด • Epidural hemorrhage • Subdural hemorrhage • Subarachnoid hemorrhage • Intracerebral hemorrhage • Diffuse axonal injury เฉลย a
Trauma • Initial management* • Epidural hematoma* • Subdural hematoma* • Traumatic intracerebral hematoma • Traumatic SAH • Skull fracture • Sequalae
Trauma • Initial management • ABCDE • Don’t miss! • Collar (primary survey = A) • ET tube in GCS ≤ 8 (primary survey = D) • Search for other bleeding site in hypotensive patient • GCS (Must remember!)
Trauma โจทย์ short essay: moderate HI in rural hospital
Trauma Glassow Coma scale
การดูแลผู้ป่วย Head Injury ABCDEs, C spine protection Resuscitation ประเมิน GCS GCS 13-15 Mild HI GCS 9-12 Moderate HI GCS < 9 Severe HI พิจารณา O2 mask c bag IV fluid พิจารณา Endotracheal tube Hyperventilation ** Mannitol/osmolar Rx ** • ประเมิน risk Mild HI • D/C • Admit observe • CT Refer
TraumaRisk factors for Intracranial lesion for Mild HI • Clinical findings • GCS < 15 หลัง 1-2 ชั่วโมง* • Amnesia • ปวดศีรษะ • อาเจียน • มีประวัติหมดสติ • มี Sign ของกะโหลกแตก (skull Fx (Skull Base/Valve) • ตรวจพบความผิดปกติทางระบบประสาท* • Risk factors • อายุ > 60 • Coagulopathy (Warfarin, Hemophilia,etc) • ชัก* • ดื่มสุรา/ใช้สารเสพติด • มีกลไกการบาดเจ็บที่รุนแรง เช่น โดนรถชนขณะเดินถนน
Trauma • Epidural Hematoma (EDH) • Associated with skull fracture • Classic: Middle meningeal artery tear • Lens shape/biconvex • Lucid interval* • Rapidly fatal • Good prognosis if proper management
Trauma • Subdural hematoma (SDH) • Venous tear/ brain laceration • High morbidity/mortality due to underlying brain injury • Crescent – concaved shape • Counter coup
Trauma • Chronic Subdural hematoma (CSDH) • Elderly, alcohol abuse, coagulopathy • Motor oil fluid, no clot • Minimal or no Hx of injury • Insidious onset • Minor symptoms hemiplegia/seizure
Trauma • Skull Fracture • Skull Fx ↑ risk of intracranial bleeding 5 times • Skull base fracture • CSF rhinorrhea, otorrhea • Battle’s sign, Raccoon’s eye (anterior skull base) • Facial weakness (petrous part of temporal bone)
Trauma Sequelae of head injury • Increased intracranial pressure (> 20 mmHg) • General: sedation, analgesia, elevate head, avoid hypoxia • Ventricular drainage • Mannitol • Hyperventilation • 2nd tier • Phenobarb coma • Decompressive craniectomy
Trauma Sequelae of head injury • Electrolyte imbalance – hyponatremia • Seizure • Antiepileptic drug - ↓ early seizure • Prophylaxis 7 days • I/C: GCS≤10, intracranial lesion, penetrating injury, depressed skull fracture • Carotid-cavernous fistula • Posttrauma 2-3 mo • Unilateral chemosis, proptosis • Bruit/thrill at the orbit • Ix: angiography • Management: balloon embolizaion
Herniation syndrome • Central • Diencephalon tentorial • Chronic • Pupils: SRTL Fixed • Uncal** • Uncus and hippocampal gyrus over tentorium • CN III compression unilateral pupil ↑, hemiparesis • Consciousness preserved in early stages • Classic for EDH
Herniation syndrome • Cingulate (subfalcine H): • asymptomatic except ACA kink, warning of impending transtentorial H. • Upward • posterior fossa mass + ventriculostomy • Tonsillar • Posterior fossa mass + LP
Tumor Supratentorial • Gliomas • Astrocytoma • Oligodendrogliomas • Ependymomas • Meningiomas • Sellar and suprasellar • Pituitary adenomas • craniopharyngiomas Infratentorial • Medulloblastoma (Ped) • Cerebellar astrocytoma • Brainstem gliomas • CP angle tumor • Vestibular schwannoma (acoustic neuromas) • Meningiomas • Meningiomas
Tumor • Most common brain tumor • Metastasis • Most common primary brain tumor • Astrocytoma • Most common primary brain tumor in children • Medulloblastoma Glioblastomamultiforme • Grade IV of astrocytoma • Poor prognosis. 2 yr survival 11 mo for total resection
Tumor • DDx for patient with progressive hemiparesis and IICP • Supratentorial tumor (Metas, gliomas, meningioma, etc) • Brain abscess (ped. With rt to lt shunt eg TOF) • DDx for patient with bitemporalhemianopia => sellar and suprasellar tumor • Pituitary adenoma • Craniopharyngioma • Meningioma
Hydrocephalous • Mechanism • Obstruction at CSF pathway: • Obstructive hydrocephalous • CSF pathway: tumor, blood, etc • Obstruction at arachnoid granulation • Communicating hydrocephalous • Overproduction: choroid plexus papilloma • Treatment • Remove etiology • Drainage • Ventriculostomy (temporary) • Shunting • VP shunt • VA shunt • Ventriculo-pleural shunt