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Delve into the captivating story of DNA's double helix structure and the ethical controversies surrounding its discovery by Rosalind Franklin. Uncover the intense scientific competition, the impact on society, and the significant role of women in science. Explore the different scientific approaches and the importance of responsible conduct in the pursuit of knowledge.
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Untold Story of Double-Helix Discover (Rosalind Franklin) & Scientific Ethics 吳耿志 Feb. 19, 2011 West Windsor, NJ
1962 Nobel Prize in Chemistry James Watson, Francis Crick, Maurice Wilkins • DNA structure Double helix • 1962 Nobel Prize in Chemistry James Watson, Francis Crick, Maurice Wilkins • DNA structure Double helix
1951, Franklin, Gosling First hint of helix • 1951, Franklin DNA in crystal, X-ray studies • 1951, Franklin single helix paper, careless handling • X-ray source & equipment • 1951, Franklin met Linus Paulin • 1951, Wilkins/Stokes “calculate”helix, not publish • 1952, Franklin sharp picture, Photo 51
1952, Watson/Crick Build model • 1952, Wilkins began to visit Crick (rival), Crick talked • to Watson; Watson got (stole) confidential report • 1-1953, Franklin, her note read w/o her consent, Wilkins revealed stunning “hint” to Watson; uninvited Watson saw Franklin’s photo. • 2-1953, Wilkins gave more keys to Watson • 2-28-1953, Crick major finding • 3-07-1953, Watson/Crick Model all done
1956 summer, Franklin California, sharp pain. • 9-1956, Franklin surgery, ovary cancer confirmed • 3-1957, Franklin cancer spread • 1958, Franklin Died.
Scientific spirit, competition, ethics, and conducts. • DNA impact on life and human society. • Female role in science; Madam Curie. • Scientific approaches: Intuitive, Imagination, Evidence • Writing: Permanent record, knowledge propagation