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Rosalind Franklin and Maurice Wilkins. James WATSON and Francis CRICK. D N A. Deoxyribonucleic acid It’s a polymer 3 parts: sugar, base, phosphate Sugar: deoxyribose Bases: 2 classes-purines (AG) and pyrimidines (CT). Purines. Pyrimidines. The DNA Song .
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D N A • Deoxyribonucleic acid • It’s a polymer • 3 parts: sugar, base, phosphate • Sugar: deoxyribose • Bases: 2 classes-purines (AG) and pyrimidines (CT)
The DNA Song • We love DNA made of nucleotides • Sugar, phosphate and a base • Binded down one side. • Adenine and thymine make a lovely pair • Cytosine without guanine would feel very bare. • (tune of Row, Row, Row Your Boat)
Important because…. • In REPLICATION, DNA polymerase can only add nucleotides to the free 3 ‘ end, NEVER EVER EVER to the 5’ end
Prokaryotic vs. Eukaryotic DNA • Pro—long double helix with its ends joined to form a circle • Eu-arranged in chromosomes • PRO EU