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Shock Diagnosis & Treatment. 台大醫院 外科加護病房 柯文哲 醫師. Three Tasks in SICU. Shock ? resuscitation 2 underlying problems ? treatment 3 nutrition ? support (metabolic support vs nutritional support). Shock or Not?. Shock. Inadequate tissue perfusion.
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Shock Diagnosis & Treatment 台大醫院 外科加護病房 柯文哲 醫師
Three Tasks in SICU • Shock ? resuscitation 2 underlying problems ? treatment 3 nutrition ? support (metabolic support vs nutritional support)
Shock Inadequate tissue perfusion
1. What is the adequate tissue perfusion? 2. What is the optimal cardiac output for a patient at a specific time? For example: A patient with acute nercotizing pancreatitis?
Definition of Shock Shock is a state of inadequate tissue perfusion 1 decreased tissue perfusion 2 inadequate tissue metabolism
Diagnosis of Shock • symptom & sign • vital sign (BP, HR, RR) • ABG • urine output • cardiac output • SvO2 (mixed venous oxygen saturation) • serum lactate • tonometry
Symptom & Sign Clinical finding: color, temp., pulse, capillary refilling conscious level mental status: clear even in very low C.O. state but maybe confused in early sepsis
Vital organs: brain, heart, lung棄車保帥:divert blood flow to vital organsvessels in vital organs: no -receptorssympathetic tone blood vessel constriction except in vital organs
Symptom & Sign Concept of vital organs: brain, heart, lung Concept of compensation: sympathetic tone perfusion to vita organs skin cool, pale GI paralysis, bleeding, “translocation” kidney oliguria
Symptom & sign • Disadvantages: • Too late to be effective • Subjective • Not quantified • Unreliable in modern ICU
Vital Signs HR, BP, RR Disadvantages: • large overlap between normal & abnormal • when obvious (too late)
BP = CO × SVRV = I × R 相信血壓 一定會倒楣
Vital Sign • Advantages: • Quantified, objective number • Automatic, computerized • Continuous --> trend analysis, not single value
Blood Gas Analysis pH, BE • intermittent measurement • pH.: A real vital sign change only in decompensated state
Basic Model in Critical Care survive success stress => compensation failure death PH in ABG
Urine Output • Advantages: • No instrument required (one Forley tube) • Simple and easy • Real time ( rapid reflection of renal perfusion) • Allow trend analysis
Urine Output NTUH SICU routine: U/O record q1h
Urine Output Normal heart, kidney, endocrine, volume status normal urine output ( p q q p ) • too many interfering factors: renal diseases, diuretics, mannitol, glycerol, hyperglycemia, DI, ATN diuretic phases • awkward in children e.g. 3 cc/hr • labor-intensive
Cardiac Output Method: • Thermodilution (intermittent, continuous) • Pulse contour (PiCCO) • Bioimpedance • Indicator-thermodilution (COLD)
- T time CO = Indicator - thermodilution
a b c d e a b c d Noise, random, summation
Cardiac Output • Intermittent: cold water injection • continuous: heating wire pulse contour impedance
Tissue Perfusion demand supply
SaO2 VO2 C.O. SvO2 Hb