1 / 12

Comparison of early results of posterior capsule opacification in eyes with Steroid induced cataracts-A Case Control st

Comparison of early results of posterior capsule opacification in eyes with Steroid induced cataracts-A Case Control study. Dr.Gauri Shah, MS Dr. Vaishali A. Vasavada , MS Dr.Mamidipudi R Praveen, DOMS Dr. Abhay R. Vasavada , MS, FRCS (England) Dr.Samaresh Srivastava, DNB .

marlon
Download Presentation

Comparison of early results of posterior capsule opacification in eyes with Steroid induced cataracts-A Case Control st

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Comparison of early results of posterior capsule opacification in eyes with Steroid induced cataracts-A Case Control study Dr.Gauri Shah, MS Dr. Vaishali A. Vasavada , MS Dr.Mamidipudi R Praveen, DOMS Dr. Abhay R. Vasavada , MS, FRCS (England) Dr.Samaresh Srivastava, DNB Iladevi Cataract & IOL Research Centre, Ahmedabad,India The authors have no financial interest

  2. Aim Materials and Methods To compare postoperative PCO development between cataractous eyes that had a history of steroid usage and those that did not • Study design : Prospective case-control study . • Study Population: • Cases : n=30patients with posterior subcapsular cataract with a history of steroid • intake in oral, inhaled, injectable, or topical forms for ≥4 months. • Controls :n=60 Age – matched healthy individuals with a posterior- subcapsular • cataract. • Phacoemulsification with single-piece hydrophobic acrylic (SN60AT)IOL • implantation in cases and controls. • Digital retro-illumination images were captured at 1 month and 1 year post- • operative. Posterior Capsule Opacification(PCO) was evaluated using the EPCO • 2000 software. • Exclusion Criteria :Glaucoma , high myopia (axial length > 27.0 mm), ocular • disorders , previous ocular surgeries , and pupil dilatation less than 7 mm .

  3. Distribution of disease

  4. Distribution of administration of various modalities of steroids

  5. Primary Observations • The amount of PCO was measured using the EPCO 2000 software and reported in terms of EPCO score and EPCO area • PCO measurements were done within the capsulorhexis margin and also the central 3 mm of the optic area. Secondary Observations • Log MAR Visual Acuity • Nd:YAG capsulotomy rates . Results

  6. Results : Comparison of PCO within the Capsulorhexis margin

  7. Results : Comparison of PCO within Central 3 mm area at 1 Year

  8. Secondary Observations Mean Log MAR visual acuity at the 1 year follow-up Nd: YAG laser capsulotomies at 8.2 months follow –up :

  9. Case Baseline 1 Year Control 1 Year Baseline

  10. Total Cover Baseline 1 Year Partial Cover Baseline 1 Year

  11. Mansfield KJ, Cerra A Effects of dexamethasone on posterior capsule opacification-like changes in a rat lens explant model Mol 2004; 10:728-37 Conclusion:Lens cell behavior in this PCO model was significantly affected by inclusion of DEX, highlighting the possibility that its use as an anti-inflammatory at the time of cataract surgery may influence PCO development Zaczek A , Zetterstrom C Posterior capsule opacification after phacoemulsification in patients with postoperative steroidal and nonsteroidal treatment J Cataract Refract Surg. 2004; 30:316-20 Conclusion : Topical installation of diclofenac , dexamethasone or placebo in the immediate period after phacoemulsification and IOL implantation did not seem to influence the formation of PCO 2 years after cataract surgery • Neumayer T, Beuhl W, Findl O • Effect of topical prednisolone and diclofenac on the short-term change in • morphology of posterior capsular opacification. • Am J Ophthalmol. 2006 Oct;142(4):550-6 • Conclusion: Topical prednisolone and diclofenac do not influence the short-term • change of Elschnig pearls. Elschnig pearls disappear and appear within days. The • degree of progression and regression varies greatly among eyes

  12. Conclusion Steroid induced PSC was associated with a higher incidence of PCO after cataract surgery at the one year follow-up

More Related