Ivan Zivkovic & Farid Amirouche , Mechanical Eng.; Mark Gonzalez, Orthopedic Surgery

1. Effects of Bone Mineral Density and Surgical Technique on Stability of Acetabular Cup after Total Hip Replacement Ivan Zivkovic & FaridAmirouche, Mechanical Eng.; Mark Gonzalez, Orthopedic Surgery Primary Grant Support: Zimmer Orthopedic • Total hip replacement surgery has become a common procedure to alleviate pain caused by osteoarthritis, rheumatoid arthritis, fractures, and other hip related problems for patients over 55 years of age. • With the aging of the global population, the demand for hip replacements is increasing, along with the required clinical lifetime. • The goal of this research is to study the effect of aging and surgical technique on stability of a hip prosthesis and ultimately to improve durability of hip joint prosthesis. • Experimental cadaveric study was conducted to measure initial relative micromotion at the prosthesis/bone interface and to investigate the effect of bone density and surgical technique on the early micromotion at the interface that may predispose to a prosthesis loosening. • Sensor technology was used to capture the micromotion of acetabular prosthesis • Image-processing package (SeScan 3.0) was designed to generate a 3-D bone geometry and material distribution from ST scan and MRI data. • Parametric patient based finite element model, validated with experimental results, was developed to further analyze the conditions affecting the initial stability and loosening of the interface for different loading conditions. • Patient specific computer system is developed which couples clinical imaging with finite element method • This increased interpretive power has the potential to streamline biomedical diagnosis, analysis, non-invasive surgical planning and most importantly computer-assisted surgery • At the initial clinical consultation proposed system would warn orthopedic surgeon of any anatomical abnormalities that could jeopardize the implant fixation, helps in determining optimal positioning of the prosthesis, insertion method, etc. which leads to reduction of operating time and to enchased patient care.