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Pharmacology I

Pharmacology I. Note Cards. Drug of choice for treatment of postoperative non-obstructive urinary retention. Bethanechol. Drug of choice for treatment of myasthenia gravis. Pyridostigmine. Drug of choice for diagnosis of Myasthenia gravis. Edrophonium.

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Pharmacology I

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  1. Pharmacology I Note Cards

  2. Drug of choice for treatment of postoperative non-obstructive urinary retention • Bethanechol

  3. Drug of choice for treatment of myasthenia gravis • Pyridostigmine

  4. Drug of choice for diagnosis of Myasthenia gravis • Edrophonium

  5. Drug of choice for treatment of cholinesterase inhibitor toxicity • Atropine

  6. Drug of choice for treatment of 1st or 2nd degree A/V block • Atropine

  7. Drug of choice for treatment of motion sickness • Scopolamine

  8. Rebound tachycardia occurs with withdrawal of these drugs • Non-selective beta blockers • propranolol • timolol • sotalol

  9. Drug of choice for treatment of acute anaphylactic shock • Epinephrine

  10. Drug of choice for treatment of 3rd degree A/V block • Epinephrine

  11. Better than atropine as a bronchodilator • Ipratropium

  12. Best drug to use in examination of glaucoma patients • Phenylephrine--does not cause cycloplegia

  13. Second choice for treatment of cholinesterase inhibitor toxicity • 2-PAM

  14. Drug of choice for treatment of glaucoma without cycloplegia • Timolol

  15. Most effective expectorant • Guaifenesin

  16. Drug of choice for treatment of glaucoma in a broncho-asthmatic patient • Betaxolol

  17. Direct-acting Parasympathomimetics • Carbachol • Bethanechol • Muscarine • Pilocarpine

  18. Drug of choice for treatment of acute wide angle glaucoma • Pilocarpine

  19. Is Bethanechol a TERT or a QUAT? • QUAT

  20. Is Pilocarpine a TERT or a QUAT? • TERT

  21. Reversible indirect-acting Parasympathomimetics • Physostigmine • Neostigmine • Edrophonium • Pyridostigmine • Demecarium

  22. Irreversible indirect-acting Parasypathomimetics • Isoflurophate • Echothiophate • Dichlorvos • Trichlorfon

  23. Tertiary Parasympatholytics • Atropine • Scopolamine • Dicyclomine

  24. Antagonist of atropine • Physostigmine

  25. Quaternary Parasympatholytics • Glycopyrrolate • Propantheline • Ipratropium

  26. Mydriatic Parasympatholytics • Atropine • Scopolamine • Cyclopentolate • Homatropine • Tropicamide

  27. Selective M1 blocker • Pirenzepine

  28. Selective M4 blocker • Tropicamide

  29. Name the major muscarinic antagonist • Atropine

  30. Ganglionic stimulants (at small doses) • Acetylcholine • Nicotine

  31. Depolarizing ganglionic blockers • Acetylcholine • Nicotine

  32. Competitive ganglionic blockers • Hexamethonium • Mecamylamine • Propantheline • Trimethaphan

  33. Drug of choice for treatment of nicotine poisoning • Mecamylamine--competitive ganglionic blocker

  34. Alpha -1 selective agonists • Phenylephrine • Methoxamine

  35. Beta-2 selective agonists • Albuterol • Terbutaline • Metaproterenol • Clinbuterol

  36. Indirect-acting Parasympathomimetics • physostigmine • neostigmine • edrophonium • pyridostigmine • demecarium

  37. Ophthalmic organophosphates • Isoflurophate • Echothiophate

  38. Anthelmintic organophosphate • Dichlorvos

  39. Preanesthetic, bronchodilator, GI antispasmodic • Glycopyrrolate

  40. T or F: Propantheline blocks only muscarinic receptors • F--it blocks ganglionic nicotinic receptors also (a parasympatholytic)

  41. Catecholamine Sympathomimetics • Epinephrine • Norepinephrine • Isoproterenol • Dopamine • Dobutamine

  42. Epinephrine is an agonist at what adrenergic receptors? • alpha 1 • alpha 2 • beta 1 • beta 2

  43. Norepinephrine act as agonist of what adrenergic receptors? • alpha 1 • alpha 2 • beta 1

  44. A catecholamine that can cause reflex bradycardia • Norepinephrine

  45. Isoproterenol act as agonist on what adrenergic receptors? • beta 1 • beta 2

  46. Dopamine acts as agonist at what receptors? • Dopaminergic • alpha 1 • alpha 2 • beta 1

  47. Dobutamine acts as agonist on what receptors? • beta 1 (mainly) • beta 2 & alpha (minor)

  48. Dopamine’s 2 most useful effects in conditions with decreased renal perfusion • Increased GFR • Renal vasodilation

  49. Catecholamines given to correct hypotension due to inhalation anesthetics • Dopamine • Dobutamine

  50. Ephedrine Pseudoephedrine Phenylpropanolamine Amphetamine Cocaine Monoamine oxidase inhibitors Phenylephrine Methoxamine Albuterol Terbutaline Metaproterenol Non Catecholamines

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