190 likes | 598 Views
Trichuriasis. Abigail Nix Tuesday, April 3 rd , 2012 Biology 402 UNC Chapel Hill. Trichuriasis is one of the seven most prevalent Neglected Tropical Diseases. WHO. WHO.
E N D
Trichuriasis Abigail Nix Tuesday, April 3rd, 2012 Biology 402 UNC Chapel Hill
Trichuriasisis one of the seven most prevalent Neglected Tropical Diseases WHO WHO
NTDs coexist with poverty because they thrive where access to clean water and sanitation are limited and people live without protection from disease vectors. iconsinmedicine.wordpress.com
Trichuriasis is one of the three common diseases caused by soil-transmitted helminths Forgotten people, forgotten diseases
Approximately 604-795 million people in the world are infected with whipworm WHO 2002
Trichuriasis is caused by the parasitic nematode Trichuristrichiura Bodyfixer.com
Trichuriasis is transmitted through the oral-fecal route Sabin.org handwashingforlife.com
UnembryonatedTrichuris eggs must develop in the soil for at least 2 weeks Stanford.edu naturalhealthtechniques.com
Two types of Trichuriasis infection: heavy and light smartplanet.com
A stool sample is used to diagnose trichuriasis Wikipedia.org
Trichuriasis is one of the neglected tropical diseases that can be controlled by mass drug administration cdc.gov
Three first line medications for trichuriasis: mebendazole, albendazole and ivermectin Stanford.edu fredunpharmaceuticals.com Indiamart.com
Benzimidazoles inhibit the polymerization of tubulin and assembly of tubulin into microtubules Stanford.edu Cureforneedy.org
Benzimidazoles inhibit the polymerization of tubulin and assembly of tubulin into microtubules Stanford.edu Cureforneedy.org Ivermectin binds to and deactivates glutamate-gated chloride channels Filariajournal.com
Prevention measures for trichuriasis focus on basic sanitation and educational efforts as well as mass drug administrations Stanford.edu
Could whipworm and other helminth infections be used as future therapeutic treatments? landesbioscience.com
Summers R W et al. Gut 2005;54:87-90 Fleming J O et al. Sumers R W et al.
References "About the Neglected Tropical Disease Program." NTD Program: Neglected Tropical Diseases. USAID, 28 Mar. 2012. Web. <http://www.neglecteddiseases.gov/index.html>. DrugBank: Open Data Drug & Drug Target Database. University of Alberta, 13 June 2005. Web. <http://www.drugbank.ca/>. Fleming, J. O., et al. "ProbioticHelminth Administration in Relapsing-remitting Multiple Sclerosis: A Phase 1 Study." Multiple Sclerosis 17.6 (2011): 743-54. Print. Hotez, Peter J. Forgotten People, Forgotten Diseases: The Neglected Tropical Diseases and Their Impact on Global Health and Development. Washington DC: ASM, 2008. Print. Hotez, Peter J. "Rescuing the Bottom Billion through Control of Neglected Tropical Diseases." Lancet 373 (2009): 1570-575. Print. Summers, R. W., et al. "TrichurisSuis Therapy in Crohn's Disease." GUT 54 (2005): 87-90. Print. Summers, R. W. , et al. "TrichurisSuis Therapy for Active Ulcerative Colitis: A Randomized Controlled Trial." Gastroenterology 128.4 (2005): 825-32. Print. "Trichuriasis." Centers for Disease Control. 2 Nov. 2010. Web. <http://www.cdc.gov/parasites/whipworm/>.