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Mutation Notes

Mutation Notes. What is a mutation?. A change in the genetic sequence or chromosome. What is a mutagen?. Mutagen examples?. Smoking, drinking, UV light, radon. GENETIC. Two Major Types of Mutations. Chromosomal: changes occur in part of the chromosome. 2. DNA/Nucleotide:

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Mutation Notes

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  1. Mutation Notes

  2. What is a mutation? A change in the genetic sequence or chromosome What is a mutagen? Mutagen examples? Smoking, drinking, UV light, radon GENETIC

  3. Two Major Types of Mutations Chromosomal: changes occur in part of the chromosome 2. DNA/Nucleotide: changes occur within a single nucleotide

  4. Types of DNA/Nucleotide Mutations A Point mutation is a single nucleotide base changein a gene's DNA sequence AFrameshift mutation results from either the addition or deletion of one nucleotide base.

  5. 1. Missense: One or more amino acids is changed in the amino acid sequence- changing the protein made 2. Nonsense: A stop codon occur early, stopping the protein from being made, resulting in no protein made 3. Silent: The mutation results in a different codon, but the codon codes for the same amino acid, resulting in the same protein being made

  6. Types of Chromosomal Mutations Inversion: reversesthe direction of parts of chromosomes – happen within one chromosome

  7. Types of Chromosomal Mutations 2. Translocation: when part of one chromosome breaks off and attaches to another – happens with non homologous chromosomes

  8. Types of Chromosomal Mutations 3. Deletion: involves the loss of all or part of a chromosome

  9. Types of Chromosomal Mutations 4. Duplication: produces extra copies of parts of a chromosome or entire chromosome

  10. Apoptosis- cell suicide

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