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By: Kevin Liu, Toan Nguyen, Serhat Yuksel

Thalassemia. By: Kevin Liu, Toan Nguyen, Serhat Yuksel. What is Thalassemia. Thalassemia is an inherited autosomal recessive blood disease. A person with Thalassemia doesn’t have the ability to produce enough hemoglobin or red blood cells to carry oxygen through the body.

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By: Kevin Liu, Toan Nguyen, Serhat Yuksel

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  1. Thalassemia By: Kevin Liu, Toan Nguyen, SerhatYuksel

  2. What is Thalassemia • Thalassemia is an inherited autosomal recessive blood disease. • A person with Thalassemia doesn’t have the ability to produce enough hemoglobin or red blood cells to carry oxygen through the body. • There are two main forms of Thalassemia, alpha-and beta-.

  3. What is Alpha • Alpha is one of the two major forms of Thalassemia. • Alpha is common in people of Western African descent and can be found in populations in Africa and America today.

  4. What is Beta • Beta is one of the two major forms of Thalassemia. • Beta is common among Mediterranean people, and this geographical area is responsible for its’ naming: Thalassa is Greek for the sea, Haema is Greek for blood. • The highest concentrations of Thalassemia are found in Greece and coastal regions in Turkey.

  5. How is Thalassemia Inherited • The parents who carry the mutated Thalassemia gene can pass it down to the child. Both Alpha and Beta are inherited the same way. • A child that inherits one mutated gene is considered to be a carrier. Most carriers lead healthy lives.

  6. Medication for Thalassemia • The medication for Thalassemia depends on the type of Thalassemia and on how severe it is. A little medication is needed even for minor Thalassemia. • A blood transfusion is occasionally needed, usually after some kind of surgery, giving birth, or if you develop an infection. More serious forms of Thalassemia usually require more frequent medications.

  7. Side Affects of Thalassemia Medication • Over a certain period of time, blood transfusions can cause a build up of iron in your blood. This can damage your heart, liver, and other organs. • To get rid of extra iron in your body you will need to take a different type of medication called “Iron Chelators”.

  8. What causes Thalassemia • Thalassemia is caused by a disruption in hemoglobin synthesis.

  9. What is Hemoglobin • Hemoglobin is an iron-containing metalloprotein.

  10. What Role does the Hemoglobin play • Hemoglobin transports oxygen from the lungs to body tissues, releases the oxygen for the use of cells, and then returns the carbon dioxide made in the tissues to the lungs to be exhaled.

  11. Thank You

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