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Overview of the Chemical Threat Laboratory of Texas

Overview of the Chemical Threat Laboratory of Texas. William Edgemond, Ph.D. Texas Department of State Health Services October 2013. Course Objectives. Introduction and Background Who We Are What We Can Do What We Want You to Do. Chemical Threats. Laboratory Response Network.

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Overview of the Chemical Threat Laboratory of Texas

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  1. Overview of the Chemical Threat Laboratory of Texas William Edgemond, Ph.D. Texas Department of State Health Services October 2013

  2. Course Objectives • Introduction and Background • Who We Are • What We Can Do • What We Want You to Do

  3. Chemical Threats

  4. Laboratory Response Network International network of laboratories to respond quickly to high priority public health emergencies, such as biological, chemical, and radiological threats, through training, rapid testing, timely notification and secure messaging of laboratory results.

  5. LRN-C Structure • Level 1 • 10 Labs • Level 2 & Level 3 Activities • National Surge Capacity • Core Methods & Add’l Methods • Additional Personal & Instruments • Level 2 • 34 Labs • Level 3 Activities • Core Methods • State/Local Response Capacity • Level 3 • 9 Labs • Competency in collecting and shipping clinical samples • Comprehensive response plan CDC

  6. US Chemical Threat Labs        Level 1   Level 2  Level 3

  7. Course Objectives • Introduction and Background • Who We Are • What We Can Do • What We Want You to Do

  8. Personnel • Dr. Bill Edgemond Team Lead/Chemical Threat Coordinator • Jim BarnesChemist • Jocelyn Hover-JeansonneChemist

  9. How We Will Respond • Can easily handle a large number of samples utilizing Lab Check-in personnel and space

  10. Types of Samples • Clinical Samples • Blood • Urine • Environmental/White Powders

  11. Clincal Methods • CAP/CLIA Accredited Lab • 11 Methods • Developed by CDC • 3 GC/MS Methods • 4 LC-MS/MS Methods • 3 ICP-MS Methods • 1 LC-ICP-MS Methods

  12. Instrumentation & Capabilities • Biosafety L2 Hood • Chemical Hoods • Automated Liquid Handler • Bar Code Reader • LIMS

  13. GC-MS • Cyanide in Blood • Volatile Organic Compounds in Blood • Tetramine in Urine

  14. ICP-MS • Cadmium, Lead, & Mercury in Blood • Trace Elements in Urine (Be, Co, Mo, Cd, Sb, Cs, Ba, W, Pt, Tl, Pb, U) • Arsenic & Selenium • LC-MS-ICP • Lewisite (Chlorovinylarsonous acid)

  15. LC-MS/MS • Abrine/Ricinine • Organophosphorous Nerve Agent Metabolites • Tetranitromethane Metabolite (HNPAA) • Monofluoroacetate/ Monchloroacetate

  16. Unknowns/White Powders • Typical submitted by FBI • Cleared by Bio Threat • Classify type of compound

  17. Texas CT Lab • Know we’re here. • Know what we can do. • Share that with labs, hospitals and first responders across the state.

  18. Unknowns/White Powders • FT-IR • FT-IR Microscope • XRF • Geiger Counter • Volatiles Detector • Wet Chemistry Tools

  19. CT Lab Contact Info • 512-458-7270—Direct Lab Phone. • 512-689-9945—24-hour Emergency Phone. • William.edgemond@dshs.state.tx.us –Chemical Threat Coordinator • http://www.dshs.state.tx.us/lab/epr.shtm --DSHS Chemical Emergency Website • http://emergency.cdc.gov/chemical/lab.asp --CDC Chemical Emergency Website

  20. Texas CT Lab

  21. Questions

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