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Mw W.Z. 1984. Poli dermatologie Roodheid coeur ; wisselend aanwezig, erytheem + papels Tevens sinds 1 jaar haarverlies eci ; bij wassen vele haren los, wil pruik. Lues screening POS Blot POS RPR 1:256. Lues screening +. Lues Endemische treponematose Aspecifiek Lyme ?.
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Mw W.Z. 1984 • Poli dermatologie • Roodheid coeur; wisselend aanwezig, erytheem + papels • Tevens sinds 1 jaar haarverlies eci; bij wassen vele haren los, wil pruik
Lues screening POS • Blot POS • RPR 1:256
Lues screening + • Lues • Endemische treponematose • Aspecifiek • Lyme?
The EndemicTreopnematosis; ClinicalMicrobiologyReviews, 2014
Stadia • Primaire lues (incubatie 9-90 dagen), duurt 3 weken • Secundaire luesontstaat na 2 maanden en duurt tot 4 jaar • Latente luesduurt 5-50 jaar • Tertiaire lues
Lues 2 • Jeukt niet • Symmetrisch • Koper rood • 8 weken maculae • 12 weken papels
Syphilitic alopecia • Patchy hair loss is characteristic of syphilis • The hair falls leaving small, scattered, irregularly thinned, ‘motheaten’ patches of semi-baldness. The eyebrows and beard may be affected Syphilitic alopecia may be accompanied by a more generalized, diffuse alopecia associated with generalized infection and anaemia
Behandeling • 2,4 miljoen IE penicilline imvroeg: eenmaliglaat: dag 1-8-15 • Doxycycline 2 dd 100mgvroeg: 2 wekenlaat: 4 weken • Zwangere: azithromycine • RPR / VDRL vervolgen
The limerick of syphilis • There was a young man of Black Bay,Whothoughtsyphilisjust went away,And feltthat a chancre,Was merely a canker,Acquired in lasciviousplay. • Nowfirsthegot acne vulgaris,The kind that is rampant in Paris,Itcoveredhis skin,Fromforehead to shin,And nowpeopleaskwherehishair is. • Withsymptomsincreasing in number,His aorta’s in need of a plumber,Hisheart is cavorting,Hiswife is aborting,And nowhe’sacquired a gumma. • Considerhis terrible plight,Hiseyeswon’treact to the light,His hands are apraxicHisgait is ataxic,He’sdevelopinggun-barrellsight. • Hispassions are strong, as before,Buthis penis is flaccid, and sore,Hiswifenow has tabesAnd sabre-shinnedbabies,She’sreallyworseoffthan a whore. • There are pains in hisbelly and knees,Hissphincters have gonebydegrees,Paroxysmalincontinence,With all its concomitants,Bringsonquiteunpredictable pees. • Thoughtreated in everyknownway,Hisspirochetesgrowdaybyday,He’sdevelopedparesis,ConverseswithJesus,And thinkshe’s the Queen of the May.