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Osseous Tissue (Bone Tissue). 1. Cells. Osteocytes— mature bone cells Osteoblasts— bone-forming cells (germ cells or “bud” cells) Osteoclasts —bone-destroying cells (“breakers”) A. primarily collagen fibers flexibility tensile strength (the strength to endure stretching forces)
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1. Cells • Osteocytes— mature bone cells • Osteoblasts— bone-forming cells (germ cells or “bud” cells) • Osteoclasts —bone-destroying cells (“breakers”) A. primarily collagen fibers flexibility tensile strength (the strength to endure stretching forces) B. calcium salts (hardness) contain calcium and phosphorus great compressional strength (the strength to endure squeezing forces) 2. Matrix
Bone Remodeling • constant balance of bone deposit and removal that occurs throughout your life • bone deposit occurs at a greater rate when bone is injured • bone reabsorption allows calcium of degraded bone matrix to move into the blood. About 10% of bone is replaced every year in an adult skeleton
Maintenance of Bone boneformation bonereabsorption osteoblasts osteoclasts
Control of Remodeling Hormonal • Rising blood Ca2+levels trigger the thyroid to release calcitonin • Calcitonin stimulates calcium salt deposit in bone • Falling blood Ca2+levels signal the parathyroid glands to release Parathyroid hormone (PTH) • PTH signals osteoclasts to degrade bone matrix and release Ca2+into the blood
Hormonal effects boneformation bonereabsorption osteoblasts osteoclasts Calcitonin(CT)from thyroid Parathyroidhormone(PTH)from parathyroid
Increase bone mass boneformation bonereabsorption osteoblasts osteoclasts Before age 25
boneformation bonereabsorption osteoblasts osteoclasts Age 25-50
Decrease bone mass boneformation bonereabsorption osteoblasts osteoclasts Age 50-on
Stress effects boneformation bonereabsorption osteoblasts osteoclasts Stress increases bone density