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Breaking vs. Making Fatty Acids: It s Just Not the Same

06.4.26. 2. Biotin and CO2 (again). A trifunctional protein: acetyl-CoA carboxylaseOne subunit carries the biotin, attached via the e-amino group of a lysine residueOne subunit activates CO2 by transferring it to the biotinWhich serves as a long flexible arm to carry the CO2 to the third subun

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Breaking vs. Making Fatty Acids: It s Just Not the Same

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    1. 06.4.26 1 Breaking vs. Making Fatty Acids: It�s Just Not the Same�! They occur by different processes They utilize different enzymes They occur in different cellular compartments They exploit different size �unit blocks�: 2-carbon for breakdown, 3-carbon for building And these ensure that they happen at different times�

    2. 06.4.26 2 Biotin and CO2 (again�) A trifunctional protein: acetyl-CoA carboxylase One subunit carries the biotin, attached via the e-amino group of a lysine residue One subunit activates CO2 by transferring it to the biotin Which serves as a long flexible arm to carry the CO2 to the third subunit

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