Ion Channel Screening

1. Trending Newsletters in September — Ion Channel Screening & Profiling Services About Creative Biogene Ion channels are pore-forming membrane proteins that create a gated, water-filled pore to help establish and control voltage potential across cell membranes through control of the active flow of ions between the intracellular and the extracellular environments. As key components in a wide variety of biological processes involved in rapid changes in cells, ion channels are important therapeutic targets in a range of indications, including cardiac, CNS, immune system and metabolic diseases. Video Creative Biogene has generated an extensive panel of ion channel screening assays comprising more than 80 ion channel targets and over 200 ion channel assays. In terms of conventional patch clamp electrophysiology, automated electrophysiology, and fluorescence assays, Creative Biogene can offer a wide range of binding and functional assays for ion channel assays to quickly and accurately provide results for drug discovery. Due to the development of screening technologies, a dramatically increased interest has been shown in ion channels for hit validation, potency determination, selectivity profiling and lead optimization...More Featured Products Resource- Gene Families Ion Channel Stable Cell Lines Creative Biogene has the most extensive collection of cell lines stably expressing functional ion channels, including Nav, Cav, ERG and others. These cell lines are carefully selected for optimal performance thus ensuring a high level of...Read More TRP Ion Channel Family Transient receptor potential (TRP) genes were first described in the fruit fly Drosophila melanogaster. Studies in its visual system identified a visually impaired mutant fly that had a transient response to steady light instead of the sustained electro- retinogram...More Related Services Ion Channel Screening & Profiling Services Kir Channel Family In multi-cellular organisms, cells are characterized by energetically favorable gradient moving potassium from the intracellular to the extracellular environment. Inwardly rectifying potassium-selective (Kir), channels encoded by...More Through conducting against ion channels from a large collection expressed in mammalian cells, a compound’s ion channel potency, efficacy, specificity or potential for off-target effects can also be high-throughput identified in early drug discovery at Creative Biogene...Read More Information of Upcoming Events Event Name Application Date City Event Type 3nd International Conference on Tumor & Cancer Immunology and Immunotherapy Biotechnology 2018/9/17- 2018/9/18 San Diego, California, USA Conference 2nd Annual Summit on Cell Signaling and Cancer Therapy Biotechnology 2018/9/19- 2018/9/20 Philadelphia, USA Conference Discovery on Target Biology & chemistry 2018/9/25- 2018/9/28 Boston, MA Conference 2018 ISPE Boston Product Show Biology & biopharmaceutical 2018/9/26- 2018/9/26 Gillette Stadium, Foxboro, MA Exhibition 45-1 Ramsey Road, Shirley, NY 11967, USA Tel: 1-631-626-9181 Fax: 1-631-614-7828 info@creative-biogene.com