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3D-Tomosynthesis. Richard Melpignano BME-181 11 February 2013. Breast Cancer. Most commonly diagnosed cancer and second leading cause of death in women in the U.S 220,000 diagnosed cases every year in U.S 40,000 deaths every year in U.S
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3D-Tomosynthesis Richard Melpignano BME-181 11 February 2013
Breast Cancer • Most commonly diagnosed cancer and second leading cause of death in women in the U.S • 220,000 diagnosed cases every year in U.S • 40,000 deaths every year in U.S • About one in eight women will be diagnosed with breast cancer at some point in their life
Traditional Mammography • Has been around for over 100 years • Uses X-rays to spot tumors in the breasts • Mammograms can help reduce death from breast cancer by 15% by spotting tumors early in development
Problems • Often unclear detection method • High amounts of over-diagnosis and under-diagnosis • This leads to multiple unnecessary screenings and more exposure to X-ray radiation • Limited 2-dimensional image leaves about 10% of cancers undetected • Denser breast tissue is difficult to read in some patients
New Detection Method • Mass General Breast Imaging teams began creating and designing a new breast cancer detection method over 10 years ago • Their method, Tomosynthesis, was approved by the FDA in February 2011 and has started to spread throughout the U.S • In Washington, D.C alone, over 35,000 procedures have been performed since August 2011
Tomosynthesis • Utilizes low-level X-rays to produce multiple images of the breast, layer by layer, using a swinging camera • This layering of images makes it simpler to detect normal breast structures (milk ducts, lobules, fatty tissues, etc.) from cancerous ones • X-rays are converted into limited 3-dimensional digital images for radiologists to examine • Computer Aided Detection (CAD) assists in spotting regions where cancer seems to be present • Dense tissue is more easily examined through Tomography than traditional Mammography
Mammography vs Tomosynthesis No lesion detected Lesion detected
Tomosynthesis (cont.) • Increases detection of Invasive breast cancers by 40% in comparison to 2D mammography • Total cancer detection increased from 6.1 patients per thousand to 8.0 patients per thousand (a 27% increase) • False-positive readings reduced by 15% • Uncertain readings and patient call-backs reduced by 20-30%
Tomosynthesis Problems • Tests take twice as long as mammography tests, resulting in slightly more radiation exposure. • Some calcification fields, which are precancerous indications, are more easily interpreted on 2-D mammograms • More expensive equipment and larger storage archives will be required
In The Near Future… • 3D Tomography will be added on to already existing 2D Mammography procedures in U.S hospitals • Tomography will be widely available within the next few years throughout the United States • As of now, the procedure costs $50 and is not currently covered by health insurance.
Resources • 3D Mammography: A Revolutionary Tool." 3D Mammography Revolutionary Tool for More Accurate Mammograms from Hologic.N.p., n.d. Web. 06 Feb. 2013. <http://www.hologic3d.com/content/3d-mammography-revolutionary-tool>. • Barclay, Laurie, MD. "3D Mammography May Improve Invasive Breast Cancer Detection." Medscape Medical News (15 Jan. 2013): n. pag. Medscape News Today. 13 Jan. 2013. Web. 6 Feb. 2013. <http://www.medscape.com/viewarticle/777709>. • "Breast Cancer Facts." National Breast Cancer Foundation, Inc.N.p., n.d. Web. 06 Feb. 2013. <http://www.nationalbreastcancer.org/breast-cancer-facts>. • "Breast Tomosynthesis a New 3D Mammogram - Washington Radiology Associates." Breast Tomosynthesis a New 3D Mammogram. N.p., 2012. Web. 06 Feb. 2013. <http://www.washingtonradiology.com/bca/index.asp>. • Lowe, Becky. "5 Benefits of Tomosynthesis." Block Imaging International, Inc.N.p., 18 Apr. 2011. Web. 06 Feb. 2013. <http://info.blockimaging.com/bid/47713/5-Benefits-of-Tomosynthesis-New-3D-Digital-Mammography-Technology>. • "Mammogram (screening or Diagnostic)." Massachusetts General Hospital Imaging. N.p., n.d. Web. 06 Feb. 2013. <http://www.massgeneral.org/imaging/services/procedure.aspx?id=2252>.