1 / 1

ABSTRACT

ABSTRACT. FORMULATION OF MANNITOL BASED GREEN TEA. EXTRACT LOZENGES. (The Influence of Polivinilpirolidon K-30 Concentration on Physical Tablet. Performance). The objective of this study was determining the effect of PVP K-30

mervin
Download Presentation

ABSTRACT

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. ABSTRACT FORMULATION OF MANNITOL BASED GREEN TEA EXTRACT LOZENGES (The Influence of Polivinilpirolidon K-30 Concentration on Physical Tablet Performance) The objective of this study was determining the effect of PVP K-30 concentration as tablet binder on physical performance of Green Tea Extract Lozenges. The Lozenges were prepared by wet granulation method with difference concentration of PVP K-30 (1%, 3% and 5%). The granules were compressed with hydraulic press at 1 ton pressure. Physical quality test of green tea extract lozenges had been evaluated, including hardness, friability and dissolving time. From statistical analysis, there were significant different among the formulas for the hardness, friability and dissolving time. The results showed that hardness and dissolving time of green tea extract lozenges were enhanced by increasing PVP K-30 concentration and the friability was reduced by increasing PVP K-30 concentration. From this observation, it could be concluded that mannitol based green tea extract lozenges with 1% concentration of PVP K-30 was the optimum formula. Keywords: physical performance, green tea extract, mannitol, PVP K-30 binder, lozenges, wet granulation.

More Related