1 / 29

Ion Channels defined

Ion Channels defined. Literature Grows. Early Models. KcsA K channel structures. Gulbis structure. 3 Kinds of nervous signal. AP recording. HH AP. Single Na Channels. State diagram for Na Ch. Early Models. Ion channel disease 1. Ion channel disease 2. Ionic current moving ions.

miach
Download Presentation

Ion Channels defined

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Ion Channels defined

  2. Literature Grows

  3. Early Models

  4. KcsA K channel structures

  5. Gulbis structure

  6. 3 Kinds of nervous signal

  7. AP recording

  8. HH AP

  9. Single Na Channels

  10. State diagram for Na Ch

  11. Early Models

  12. Ion channel disease 1

  13. Ion channel disease 2

  14. Ionic current moving ions

  15. Ludwig Boltzmann Question: How is the internal energy in a system containing a large number of particles (N) distributed among the particles? Ans.:there will be more particles with low energy (U) than with high Boltzmann constant (R/Na ) N N(U) = A exp -(U/ kbT) n1 n2 U U1 U2

  16. Biophysics: Nernst Potential

  17. Current-Voltage Relations E is potential in volts

  18. Membrane Capacitance

  19. Equivalent Circuits

  20. AP recording

  21. Flux coupling in a long pore Force

  22. KcsA K channel structures

  23. Na:K ATPase, a Stoichiometric Transporter Moves 3Na+ out and 2K+ in per ATP. Stoichiometry of a pump

  24. Evolutionary tree

  25. K Channel Dendrogram

  26. Three Roles of ion channels

  27. Electrical call to action

  28. Ca channel modulation

More Related