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Life Course Socioeconomic Status, Social Context and Cardiovascular Disease: The LCSES Study Kathryn Rose, PhD for The LCSES Study Team. Background. LCSES and ARIC Studies.

micah-little
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Background

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  1. Life Course Socioeconomic Status, Social Context and Cardiovascular Disease: The LCSES StudyKathryn Rose, PhDfor TheLCSES Study Team

  2. Background

  3. LCSES and ARIC Studies • As part of the ARIC study, information on mid to later life socioeconomic status (SES) was collected at each of the four examinations • As an ancillary study, LCSES collected additional information from surviving participants about earlier life SES circumstances • Individual-level SES • Place of residence

  4. LCSES Study Goals • Examine the association between SES across the life course and CVD-related outcomes • Determine the extent to which the current and historical (neighborhood) context modify the association of individual-level SES exposures and CVD events • Identify explanatory mechanisms for the SES-CVD association

  5. LCSES Questionnaire • Administered during 2001-02 ARIC annual telephone follow-up (AFU) • 44 questions about childhood and earlier adulthood social exposures • Individual-level SES • Military Service • Place of residence • Used to link participants with historical census data

  6. LCSES Participants • N = 12,716 • 80.5% of the baseline ARIC participants • Approximately 95% of cohort survivors

  7. LCSES Participant Characteristics RACE/GENDER Black Women Black Men White Women White Men 16.5% 9.0% 40.8% 33.8% AGE at BASELINE 45-49 50-54 55-59 60-64 29.5% 27.3% 23.7% 19.7%

  8. Type of Historical Data Collected Individual Level SES

  9. Individual Level Childhood SES: • Mother and father’s (or other caretaker’s) • Education • Occupation • Census-based categories analogous to those used in ARIC study • Owner vs. worker • Whether or not managed or supervised • Home ownership

  10. Recalled Individual-level SES-Related Attributes in Earlier Adulthood • Occupation at ages 30, 40, and 50 • Grouped into Bureau of Census Job Categories • Characteristics of Job • Owner vs. Worker • Managerial/Supervisory • Home ownership

  11. Type of Historical Data Collected Contextual Level (Place of Residence)

  12. Childhood Place of Residence • City / County / State of Residence during childhood • Data cleaning / editing • 3% resided outside of the US • 44% resided in the same county as in midlife • Linking with county-level census data • Chose decennial census (1930, 1940, 1950) that corresponded most closely to where participant livedat 10 years of age • Of the 12,314 participants who lived in the US as children, 99% were linked to county-level census data

  13. Distribution of Participants by Birth Cohort 4000 3500 3000 2500 Number 2000 1500 1000 500 0 1921-25 1926-30 1931-35 1936-40 1941-45 ARIC Participant’s Birth Cohort

  14. Place of Residence at Ages 30, 40, and 50 • Participants asked to provide their complete street address • Goal: link with census tract data from historical census (1960 – 1980) most closely corresponding to the given age • Only queried about address for a given age if not already in ARIC at this age

  15. Progress to Data • Strategies for working with complex historical census data have been developed • Individual and contextual / neighborhood socio-economic exposure data across the life course has been assembled for study participants • Various research projects focusing on cardiovascular disease related outcomes are in progress

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