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CytoSkeleton. By: John Mandziara. Made of. The cytoskeleton is made up of three kinds of filaments: 1. Actin Filaments (Micro) 2. Intermediate Filaments 3. Microtubules . The three parts:. Actin Filaments .
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CytoSkeleton By: John Mandziara
Made of • The cytoskeleton is made up of three kinds of filaments: 1. Actin Filaments (Micro) 2. Intermediate Filaments 3. Microtubules
Actin Filaments • Monomers of the protein actin polymerize to form long, thin fibers. These are about 8 nm in diameter and, being the thinnest of the cytoskeletal filaments, are also called microfilaments. In skeletal muscle fibers they are called thin filaments • What they do: 1. Provide strength 2. Start Motion 3. Interact with myosin (thick) for muscular contractions
Intermediate Filaments • These cytoplasmic fibers average 10 nm in diameter and thus are "intermediate" in size between actin filaments 8 nm and microtubules 25 nm as well as of the thick filaments of skeletal fibers • Types: 1. Keratins (Hair and Nails) 2. Lamins (Stabilize the inner membrane) 3.Nuerofilaments (Strengthen the long axons of neurons) 4. Vimentins (Provide mechanical strength to muscles)
Microtubules • Straight, hollow cylinders whose wall is made up of a ring of 13 "protofilaments"; have a diameter of about 25 nm; are variable in length but can grow 1000 times as long as they are wide; are built by the assembly of dimers of alpha tubulin and beta tubulin; are found in both animal and plant cells. • Grow at each end by the polymerization of tubulindimers (powered by the hydrolysis of GTP), and shrink at each end by the release of tubulindimers (depolymerization). • Two major groups: 1. Kinesins (move toward positive end) 2. Dyneins (move toward negative end)