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Trachoma

Trachoma. Elizabeth Cotton. Chlamydia trachomatis in an intracellular bacteria that causes trachoma. The pathogen lives in modified endosomes in epithelia l cells. Trachoma is transmitted by direct contact or by flies. Trichiasis causes blindness.

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Trachoma

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  1. Trachoma Elizabeth Cotton

  2. Chlamydia trachomatis in an intracellular bacteria that causes trachoma

  3. The pathogen lives in modified endosomes in epithelialcells

  4. Trachoma is transmitted bydirect contact or by flies

  5. Trichiasis causes blindness

  6. The disease is generally diagnosed by simple observation

  7. The “SAFE” strategy • S: surgery • A: antibiotic treatment • F: facial cleanliness • E: environmental changes

  8. Mass treatment with azithromycin has proven effective in many areas

  9. Overall load of C. trachomatis steadily declined over time in all age groups

  10. Active trachoma decreased over time in all age groups

  11. Combination therapy is the most common treatment of trachoma

  12. The “SAFE” strategy • S: surgery • A: antibiotic treatment • F: facial cleanliness • E: environmental changes

  13. Face washing is one way to prevent the spread of trachoma

  14. Children and women in urban areas are the most vulnerable to trachoma

  15. The “SAFE” strategy • S: surgery • A: antibiotic treatment • F: facial cleanliness • E: environmental changes

  16. 6 Million people are blind due to trachoma and 150 million people need treatment

  17. Africa and Southeast Asia have the highest rates of trachoma in the world

  18. Numerous NGOs are involved in trachoma prevention and treatment

  19. Sources • "Chlamydia and Chlamydophila." Microbiology And Immunology Online. University Of South Carolina School Of Medicine, 24 June 2010. Web. 11 Apr. 2012. <http://pathmicro.med.sc.edu/mayer/chlamyd.htm>. • "Chlamydia Trachomatis." Wikipedia. Wikipedia, 18 Mar. 2012. Web. 11 Apr. 2012. <http://en.wikipedia.org/wiki/Chlamydia_trachomatis>. • "Development Cycle of Chlamydia Trachomatis." Nature Reviews: Immunology, Feb. 2005. Web. 11 Apr. 2012. <http://www.nature.com/nri/journal/v5/n2/fig_tab/nri1551_F2.html>. • "International Trachoma Initiative." Wikipedia, 23 Feb. 2012. Web. 11 Apr. 2012. <http://en.wikipedia.org/wiki/International_Trachoma_Initiative>. • "Risk Factors." Trachoma. Mayo Clinic, 17 July 2010. Web. 11 Apr. 2012. <http://www.mayoclinic.com/health/trachoma/DS00776/DSECTION=risk-factors>. • "Trachoma." Prevention Of Blindness And Visual Impairment. World Health Organization, n.d. Web. 11 Apr. 2012. http://www.who.int/blindness/causes/trachoma/en/index.html. • "Trachoma." Water Related Diseases. World Health Organization, 2001. Web. 11 Apr. 2012. <http://www.who.int/water_sanitation_health/diseases/trachoma/en/index.html>. • "Trachoma." Wikipedia, 23 Mar. 2012. Web. 11 Apr. 2012. <http://en.wikipedia.org/wiki/Trachoma>. • Newman, Mark. "Blinding Disease." World Mapper, n.d. Web. 11 Apr. 2012. <http://www.worldmapper.org/posters/worldmapper_map234_ver5.pdf>. • Soloman, Anthony W. "Mass Treatment with Single-Dose Azithromycin for Trachoma." The New England Journal of Medicine 351.19 (2004): 1962-1971. Web. • Solomon, Anthony W. "Diagnosis and Assessment of Trachoma." Clinical Biology Reviews. American Society Of Microbiology, n.d. Web. 11 Apr. 2012. <http://cmr.asm.org/content/17/4/982.full#sec-4>. • Trachoma Control: A Guide for Programme Managers. Geneva, Switzerland: World Health Organization, 2006. PDF file. <http://www.who.int/blindness/publications/tcm%20who_pbd_get_06_1.pdf>. • West, Sheila K., Nathan Congdon, Sidney Katala, and Lisa Mele. "Facial Cleanliness and Risk of Trachoma in Families." Epidemiology and Biostatistics 109.June (1999): 855-857. Web. 11 Apr. 2012. • http://www.who.int/blindness/causes/trachoma_documents/en/index.html • Unite For Sight Web. 11 Apr 2012 http://www.uniteforsight.org/about-us/history • “Trachoma” The Carter Center. Web. 11 Apr 2012. <http://www.cartercenter.org/health/trachoma/index.html>

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